Human Smad7/MADH7 (Mothers Against Decapentaplegic Homolog 7) ELISA Kit

Human Smad7/MADH7 (Mothers Against Decapentaplegic Homolog 7) ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-HUES02058.96 96 assays -

9 - 20 business days*

708.00€
 
ELISA Type: Sandwich. Sensitivity: 0.094ng/mL. Range: 0.156--10ng/mL. Protein function:... more
Product information "Human Smad7/MADH7 (Mothers Against Decapentaplegic Homolog 7) ELISA Kit"
ELISA Type: Sandwich. Sensitivity: 0.094ng/mL. Range: 0.156--10ng/mL. Protein function: Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. [The UniProt Consortium]
Keywords: Smad7, SMAD7, MADH7, hSMAD7, SMAD 7, MAD homolog 8, MAD homolog 7, SMAD family member 7, Mothers against DPP homolog 7, Mothers against DPP homolog 8, Mothers against decapentaplegic homolog 7, Mothers against decapentaplegic homolog 8
Supplier: Assay Genie
Supplier-Nr: HUES02058

Properties

Application: Sandwich ELISA
Species reactivity: human
Format: Solid Phase

Handling & Safety

Storage: vT
Shipping: +4°C (International: +4°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319
P Phrases: P264, P280
Caution
Our products are for laboratory research use only: Not for administration to humans!
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