Human Robo1 / DUTT1 ELISA Kit

Human Robo1 / DUTT1 ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG82385.96 96 wells -

6 - 14 business days*

1,416.00€
 
Protein function: Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular... more
Product information "Human Robo1 / DUTT1 ELISA Kit"
Protein function: Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development (PubMed:10102268, PubMed:24560577). Interaction with the intracellular domain of FLRT3 mediates axon attraction towards cells expressing NTN1 (PubMed:24560577). In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. Plays a role in the regulation of cell migration via its interaction with MYO9B, inhibits MYO9B-mediated stimulation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA (PubMed:26529257). May be required for lung development. [The UniProt Consortium]
Keywords: ROBO1, DUTT1, H-Robo-1, Roundabout homolog 1, Deleted in U twenty twenty
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG82385

Properties

Application: ELISA
Species reactivity: human
Format: Solid Phase

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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