Human Rbx2(RNF7) ELISA Kit

Human Rbx2(RNF7) ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-HUFI03104.96 96 assays -

9 - 20 business days*

698.00€
 
Protein function: Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase... more
Product information "Human Rbx2(RNF7) ELISA Kit"
Protein function: Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription (PubMed:10851089). CRLs complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins, ARIH1 mediating addition of the first ubiquitin on CRLs targets. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents. [The UniProt Consortium]
Keywords: RNF7, RBX2, Rbx2, CKBBP1, RING-box protein 2, RING finger protein 7, Regulator of cullins 2, CKII beta-binding protein 1, Sensitive to apoptosis gene protein
Supplier: Assay Genie
Supplier-Nr: HUFI03104

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