Human PRF1 (Perforin 1) ELISA Kit

The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of PRF1 in serum, plasma and other biological fluids. Detection Range: 0.78--50ng/mL. Sensitivity: 0.47ng/mL. Protein function: Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes. [The UniProt Consortium]