Human Phospholipase A2 IIA ELISA Kit

Human Phospholipase A2 IIA ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG82428.96 96 wells -

6 - 14 business days*

1,118.00€
 
Protein function: Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in... more
Product information "Human Phospholipase A2 IIA ELISA Kit"
Protein function: Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins (PubMed:18635536, PubMed:25398877). Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 (PubMed:18635536, PubMed:25398877). Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:25398877). Induces cell proliferation in an integrin-dependent manner (PubMed:18635536). [The UniProt Consortium]
Keywords: PLA2B, PLA2G2A, NPS-PLA2, GIIC sPLA2, Group IIA phospholipase A2, Phospholipase A2, membrane associated, Phosphatidylcholine 2-acylhydrolase 2A, Non-pancreatic secretory phospholipase A2
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG82428

Properties

Application: ELISA
Species reactivity: human
Format: Solid Phase

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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