Human NSFL1C (NSFL1 cofactor p47) ELISA Kit (HUFI07476)

Human NSFL1C (NSFL1 cofactor p47) ELISA Kit from Assay Genie is a pre-coated immunoassay with a high sensitivity and broad range and has been designed to measure Human NSFL1C (NSFL1 cofactor p47) in serum, plasma & cell culture supernatant samples. The Human NSFL1C (NSFL1 cofactor p47) ELISA Kit accurately measures natural Human NSFL1C (NSFL1 cofactor p47) levels quantified versus standard curves obtained and is based on antibodies raised against a recombinant Human NSFL1C (NSFL1 cofactor p47) peptide. Protein function: Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP- mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro) (PubMed:15498563). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase (PubMed:23649807). Also, regulates spindle orientation during mitosis (PubMed:23649807). [The UniProt Consortium]