Human LTBP1 (Latent-transforming growth factor beta-binding protein 1) ELISA Kit (HUFI03563)

Human LTBP1 (Latent-transforming growth factor beta-binding protein 1) ELISA Kit from Assay Genie is a pre-coated immunoassay with a high sensitivity and broad range and has been designed to measure Human LTBP1 (Latent-transforming growth factor beta-binding protein 1) in serum, plasma & cell culture supernatant samples. The Human LTBP1 (Latent-transforming growth factor beta-binding protein 1) ELISA Kit accurately measures natural Human LTBP1 (Latent-transforming growth factor beta-binding protein 1) levels quantified versus standard curves obtained and is based on antibodies raised against a recombinant Human LTBP1 (Latent-transforming growth factor beta-binding protein 1) peptide. Protein function: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:2022183, PubMed:8617200, PubMed:8939931). Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed:8617200, PubMed:8939931, PubMed:15184403). Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta (PubMed:22278742). [The UniProt Consortium]