Human LRWD1 (Leucine-rich repeat and WD repeat-containing protein 1) ELISA Kit (HUFI03579)

Human LRWD1 (Leucine-rich repeat and WD repeat-containing protein 1) ELISA Kit from Assay Genie is a pre-coated immunoassay with a high sensitivity and broad range and has been designed to measure Human LRWD1 (Leucine-rich repeat and WD repeat-containing protein 1) in serum, plasma & cell culture supernatant samples. The Human LRWD1 (Leucine-rich repeat and WD repeat-containing protein 1) ELISA Kit accurately measures natural Human LRWD1 (Leucine-rich repeat and WD repeat-containing protein 1) levels quantified versus standard curves obtained and is based on antibodies raised against a recombinant Human LRWD1 (Leucine-rich repeat and WD repeat-containing protein 1) peptide. Protein function: Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post- replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability. [The UniProt Consortium]