Human KANK2 (KN motif and ankyrin repeat domain-containing protein 2) ELISA Kit

Human KANK2 (KN motif and ankyrin repeat domain-containing protein 2) ELISA Kit is a high quality kit for research use only from Assay Genie. The Human KANK2 (KN motif and ankyrin repeat domain-containing protein 2) ELISA Kit comes in a 96 Assays format and reacts against Human samples. We ship this kit on Gel Pack and kits should be stored at 2-8°C Protein Function: Involved in transcription regulation by sequestering in the cytoplasm nuclear receptor coactivators such as NCOA1, NCOA2 and NCOA3 (PubMed:17476305). Involved in regulation of caspase-independent apoptosis by sequestering the proapoptotic factor AIFM1 in mitochondria (PubMed:22371500). Pro-apoptotic stimuli can induce its proteasomal degradation allowing the translocation of AIFM1 to the nucleus to induce apoptosis (PubMed:22371500). Involved in the negative control of vitamin D receptor signaling pathway (PubMed:24671081). Involved in actin stress fibers formation through its interaction with ARHGDIA and the regulation of the Rho signaling pathway (PubMed:17996375, PubMed:25961457). May thereby play a role in cell adhesion and migration, regulating for instance podocytes migration during development of the kidney (PubMed:25961457). Through the Rho signaling pathway may also regulate cell proliferation (By similarity) [The Uniprot Consortium]