Human HOPX (Homeodomain-only protein) ELISA Kit (HUFI03909)

Human HOPX (Homeodomain-only protein) ELISA Kit from Assay Genie is a pre-coated immunoassay with a high sensitivity and broad range and has been designed to measure Human HOPX (Homeodomain-only protein) in serum, plasma & cell culture supernatant samples. The Human HOPX (Homeodomain-only protein) ELISA Kit accurately measures natural Human HOPX (Homeodomain-only protein) levels quantified versus standard curves obtained and is based on antibodies raised against a recombinant Human HOPX (Homeodomain-only protein) peptide. Protein function: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF- dependent cardiac-specific genes and cardiac development. Prevents SRF- dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. May act as a tumor suppressor. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding (PubMed:27708256). [The UniProt Consortium]