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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
G-HUES00296.96 | 96 assays | - |
9 - 20 business days* |
694.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
ELISA Type: CLIA. Sensitivity: 18.75 pg/mL. Range: 31.25--2000 pg/mL. Protein function: A... more
Product information "Human CYP26A1 (Cytochrome P450, family 26, subfamily A, polypeptide 1) CLIA Kit"
ELISA Type: CLIA. Sensitivity: 18.75 pg/mL. Range: 31.25--2000 pg/mL. Protein function: A cytochrome P450 monooxygenase involved in the metabolism of all-trans retinoic acid (atRA), a signaling molecule that binds to retinoic acid receptors and regulates gene transcription. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR, NADPH- ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon hydrogen bonds of atRA primarily at C-4 and C-18. Has no activity toward 9-cis and 13-cis retinoic acid stereoisomers (PubMed:22020119, PubMed:9228017, PubMed:9716180). May play a role in the oxidative metabolism of xenobiotics such as tazarotenic acid (PubMed:26937021). [The UniProt Consortium]
Keywords: | CYP26, hP450RAI, Cytochrome P450RAI, Cytochrome P450 26A1, Retinoic acid 4-hydroxylase, Retinoic acid-metabolizing cytochrome, Cytochrome P450 retinoic acid-inactivating 1 |
Supplier: | Assay Genie |
Supplier-Nr: | HUES00296 |
Properties
Application: | CLIA |
Species reactivity: | human |
Format: | Solid Phase |
Database Information
KEGG ID : | K07437 | Matching products |
UniProt ID : | O43174 | Matching products |
Gene ID | GeneID 1592 | Matching products |
Handling & Safety
Storage: | vT |
Shipping: | +4°C (International: +4°C) |
Signal Word: | Warning |
GHS Hazard Pictograms: |
|
H Phrases: | H315, H319 |
P Phrases: | P264, P280 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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