Human CYP26A1 (Cytochrome P450, family 26, subfamily A, polypeptide 1) CLIA Kit

Human CYP26A1 (Cytochrome P450, family 26, subfamily A, polypeptide 1) CLIA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-HUES00296.96 96 assays -

9 - 20 business days*

694.00€
 
ELISA Type: CLIA. Sensitivity: 18.75 pg/mL. Range: 31.25--2000 pg/mL. Protein function: A... more
Product information "Human CYP26A1 (Cytochrome P450, family 26, subfamily A, polypeptide 1) CLIA Kit"
ELISA Type: CLIA. Sensitivity: 18.75 pg/mL. Range: 31.25--2000 pg/mL. Protein function: A cytochrome P450 monooxygenase involved in the metabolism of all-trans retinoic acid (atRA), a signaling molecule that binds to retinoic acid receptors and regulates gene transcription. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR, NADPH- ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon hydrogen bonds of atRA primarily at C-4 and C-18. Has no activity toward 9-cis and 13-cis retinoic acid stereoisomers (PubMed:22020119, PubMed:9228017, PubMed:9716180). May play a role in the oxidative metabolism of xenobiotics such as tazarotenic acid (PubMed:26937021). [The UniProt Consortium]
Keywords: CYP26, hP450RAI, Cytochrome P450RAI, Cytochrome P450 26A1, Retinoic acid 4-hydroxylase, Retinoic acid-metabolizing cytochrome, Cytochrome P450 retinoic acid-inactivating 1
Supplier: Assay Genie
Supplier-Nr: HUES00296

Properties

Application: CLIA
Species reactivity: human
Format: Solid Phase

Handling & Safety

Storage: vT
Shipping: +4°C (International: +4°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319
P Phrases: P264, P280
Caution
Our products are for laboratory research use only: Not for administration to humans!
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