Human COL4A2 (Collagen alpha-2 (IV) chain) ELISA Kit

Human COL4A2 (Collagen alpha-2 (IV) chain) ELISA Kit is a high quality kit for research use only from Assay Genie. The Human COL4A2 (Collagen alpha-2 (IV) chain) ELISA Kit comes in a 96 Assays format and reacts against Human samples. We ship this kit on Gel Pack and kits should be stored at 2-8°C Protein Function: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen , Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins [The Uniprot Consortium]