Human A Disintegrin and Metalloproteinase with Thrombospondin Motifs 1 (ADAMTS1) ELISA kit

Sample Types: serum, plasma, tissue homogenates, urine Detection Range: 0.312 ng/mL-20ng/mL Sensitivity: 0.078 ng/mL Assay Principle: quantitative Measurement: SandwichAssay Time: 1-5h Sample Volume: 50-100ulDetection Wavelength: 450 nmProtein function: Cleaves aggrecan, a cartilage proteoglycan, at the '1938- Glu-, -Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover. Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture. [The UniProt Consortium]