Granzyme B (human) ELISA Kit

Diaclone ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure., Assay Range: 31.25-1000 pg/ml, Sensitivity: 20 pg/ml, Cross reaction: No cross reactivity with Trail, TNFalpha, IFNgamma, Fas, IL-1alpha, IL-4, IL-6, IL-8, IL-13, Incubation time: 3h00, Sample Types: Serum, Plasma, Cell culture supernatant, Sample Size: 100 µl Protein function: This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. [The UniProt Consortium]