DNA/RNA Oxidative Damage (Clone 7E6.9) ELISA Kit

DNA/RNA Oxidative Damage (Clone 7E6.9) ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay501130-96S 96 so-wells (96 solid wells) -

6 - 10 business days*

469.00€
Cay501130-96 96 st-wells (96 strip wells) -

6 - 10 business days*

469.00€
Cay501130-480S 480 so-wells (480 solid wells) -

6 - 10 business days*

1,875.00€
Cay501130-480 480 st-wells (480 strip wells) -

6 - 10 business days*

1,875.00€
 
DNA and RNA are damaged by oxidation during aging and in a variety of disease states including... more
Product information "DNA/RNA Oxidative Damage (Clone 7E6.9) ELISA Kit"
DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer. Guanine is the base is most prone to oxidation, and the repair processes initiated to correct the damage release multiple oxidized guanine species into the urine, including 8-hydroxyguanosine (8-OHG), 8-hydroxy-2'-deoxyguanosine (8-OHdG), and 8-hydroxyguanine. Some commercial vendors offer immunoassays that detect only 8-OHdG. Cayman's DNA/RNA Oxidative Damage (Clone 7E6.9) ELISA Kit is a competitive assay that can be used to measure both 8-OHdG and 8-OHG. Since the antibody used in the assay recognizes damaged nucleic acid species other than 8-OHdG, the value obtained with our assay will be higher than that obtained by competitor ELISAs or by LC/MS analysis that measure a single species. As such, caution is recommended when comparing results obtained from this kit to those obtained by other methods. Synonyms: DNA/RNA Oxidative Damage (Clone 7E6.9) EIA Kit, 8-Hydroxyguanosine, 8-OHG. Assay Range: 0.15-20 ng/ml. Sensitivity: 80% B/B0: 0.45 ng/ml. Mid-point: 50% B/B0: 1.25-1.75 ng/ml. Cross Reactivity: (8-hydroxy-2'-deoxyguanosine) 100%, (8-hydroxyguanosine) 100%, (8-hydroxyguanine) 0.15%, (Guanine) <0.1%, (Guanosine) <0.1%. Origin: Animal/Bovine, Animal/Eel, Animal/Mouse.
Keywords: 8-OHG, 8-Hydroxyguanosine, DNA/RNA Oxidative Damage (Clone 7E6.9) EIA Kit
Supplier: Cayman Chemical
Supplier-Nr: 501130

Properties

Application: ELISA
Reactivity: Broad (Expected: Broad)
Format: Solid Phase

Database Information

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H301, H311, H315, H316, H317, H319, H351, H361
P Phrases: P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P270, P272, P280, P301+310, P302+352, P303+361+353, P305+351+338, P308+313, P312, P321, P330, P332+313, P333+313, P337+313, P361+364, P362+364, P370+378, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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