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Item number: ARG83700.1
Protein function: Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. [The UniProt Consortium]
| Keywords: | B7DC, PD-L2, B7-DC, CD273, PD-L2, B7-DC, CD273, PDCD1LG2, PD-1 ligand 2, PD-1 ligand 2, PDCD1 ligand 2, PDCD1 ligand 2,... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83702.1
Protein function: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. [The UniProt Consortium]
| Keywords: | C5, CPAMD4, Complement C5, C5a anaphylatoxin, Complement C5 beta chain, Complement C5 alpha chain, Complement C5 alpha'... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83704.1
Protein function: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from...
| Keywords: | CRP, PTX1, C-reactive protein, C-reactive protein(1-205) |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83706.1
Protein function: Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (PubMed:7540647, PubMed:11157474, PubMed:22652417). Plays thereby an...
| Keywords: | INP10, IP-10, CXCL10, Gamma-IP10, CXCL10(1-73), C-X-C motif chemokine 10, Small-inducible cytokine B10, 10 kDa interferon... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83708.1
Protein function: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation...
| Keywords: | FBP, FBP, FOLR, FOLR1, FR-alpha, FR-alpha, KB cells FBP, KB cells FBP, Folate receptor 1, Folate receptor 1, Folate... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83711.1
Protein function: Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells,...
| Keywords: | MBL2, MBP1, MBP1, MBP-C, MBP-C, COLEC1, Collectin-1, Collectin-1, Mannan-binding protein, Mannose-binding lectin,... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83712.1
Protein function: Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in...
| Keywords: | CSF1, MCSF, CSF-1, M-CSF, Lanimostim, Macrophage colony-stimulating factor 1, Processed macrophage colony-stimulating... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83713.1
Protein function: Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. [The UniProt Consortium]
| Keywords: | MIC-B, MIC-B, MHC class I polypeptide-related sequence B, MHC class I polypeptide-related sequence B |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83715.1
Protein function: Can degrade fibrillar type I, II, and III collagens. [The UniProt Consortium]
| Keywords: | MMP8, CLG1, MMP-8, MMP-8, PMNL-CL, PMNL-CL, PMNL collagenase, PMNL collagenase, Neutrophil collagenase, Neutrophil... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83716.1
Protein function: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV,...
| Keywords: | MMP13, MMP-13, MMP-13, Collagenase 3, Collagenase 3, Matrix metalloproteinase-13, Matrix metalloproteinase-13 |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83717.1
Protein function: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. [The UniProt Consortium]
| Keywords: | SPP1, BNSP, SPP-1, SPP-1, PSEC0156, Uropontin, Uropontin, Osteopontin, Osteopontin, Nephropontin, Nephropontin, Bone... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83719.1
Protein function: Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases...
| Keywords: | p55, p60, TBPI, TNFAR, TNF-R1, TNF-RI, TNFR-I, CD120a, TNFRSF1A, Tumor necrosis factor receptor 1, Tumor necrosis factor... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*