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Item number: ARG83651.96
Protein function: Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity. {ECO:0000269, PubMed:11165938, ECO:0000269, PubMed:11292659, ECO:0000269, PubMed:16512877}. [The...
| Keywords: | ECM1, Secretory component p85, Secretory component p85, Extracellular matrix protein 1, Extracellular matrix protein 1 |
| Application: | ELISA |
| Species reactivity: | human |
1,052.00€
*
Item number: ARG83659.96
Protein function: Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria (PubMed:9468508). Also plays a role in binding of unopsonized particles by alveolar macrophages. Binds to the secretoglobin SCGB3A2 (PubMed:12847263). [The UniProt Consortium]
| Keywords: | MARCO, SCARA2, Macrophage receptor MARCO, Macrophage receptor MARCO, Scavenger receptor class A member 2, Scavenger... |
| Application: | ELISA |
| Species reactivity: | mouse |
1,052.00€
*
Item number: ARG83663.96
Protein function: Involved in transforming growth factor beta (TGF-beta)- induced smooth muscle differentiation. TGF-beta induces expression and translocation of OLFM2 to the nucleus where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to...
| Keywords: | NOE2, OLFM2, Noelin-2, Noelin-2, Olfactomedin-2, Olfactomedin-2 |
| Application: | ELISA |
| Species reactivity: | human |
1,052.00€
*
Item number: ARG83675.1
Protein function: Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed:17671174). Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from...
| Keywords: | IDO, IDO1, IDO-1, IDO-1, Indoleamine 2,3-dioxygenase 1, Indoleamine 2,3-dioxygenase 1, Indoleamine-pyrrole... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83677.1
Protein function: Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:2971451, PubMed:7617032, PubMed:10986460). Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:7673114). Plays an essential role in the IFN-gamma pathway that is...
| Keywords: | CD119, CD119, CDw119, CDw119, IFN-gamma-R1, IFN-gamma-R1, IFN-gamma receptor 1, IFN-gamma receptor 1, IFN-gamma-R-alpha... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83679.1
Protein function: This is a receptor for interleukin-3. [The UniProt Consortium]
| Keywords: | IL3R, IL3RA, CD123, CD123, IL-3RA, IL-3RA, IL-3R-alpha, IL-3R-alpha, IL-3R subunit alpha, IL-3R subunit alpha, IL-3... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83684.1
Protein function: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R,...
| Keywords: | SGRF, IL23A, IL-23-A, IL-23-A, IL-23p19, IL-23p19, IL-23 subunit alpha, IL-23 subunit alpha, Interleukin-23 subunit p19,... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83689.1
Protein function: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion, induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory...
| Keywords: | B7H2, B7-H2, CD275, B7-H2, CD275, ICOSLG, B7RP-1, B7RP-1, ICOS ligand, ICOS ligand, B7 homolog 2, B7 homolog 2, B7-like... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83690.1
Protein function: Triggers NCR3-dependent natural killer cell activation. {ECO:0000269, PubMed:19528259}. [The UniProt Consortium]
| Keywords: | B7H6, B7-H6, B7-H6, NCR3LG1, B7 homolog 6, B7 homolog 6, Natural cytotoxicity triggering receptor 3 ligand 1, Natural... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83692.1
Protein function: Shows chemotactic activity for monocytes, resting T- lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are...
| Keywords: | MIP3, CCL23, CKB-8, MIP-3, MPIF-1, CK-beta-8, CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99), C-C motif chemokine... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83693.1
Protein function: Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical...
| Keywords: | CCL25, SCYA25, Chemokine TECK, Chemokine TECK, C-C motif chemokine 25, C-C motif chemokine 25, Thymus-expressed chemokine,... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83702.1
Protein function: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. [The UniProt Consortium]
| Keywords: | C5, CPAMD4, Complement C5, C5a anaphylatoxin, Complement C5 beta chain, Complement C5 alpha chain, Complement C5 alpha'... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*