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Alternative Complement Pathway, Mouse, Assay
Item number: HYC-HIT422
The HIT422 measures the alternative pathway activity mediated via LPS. Complement deficiencies or other defects in the complement system can easily be screened by running an assay for each pathway in parallel or separately. The ELISA contains a positive control which can be used as control to ensure that the...
| Keywords: | AP, alternative pathway |
| Application: | ELISA |
| Species reactivity: | mouse |
929.00€
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Complement Pathway, Mouse, Assay
Item number: HYC-HIT423
The HIT423 contains three Complement Pathway Assays: - HIT420, Classical Complement Pathway, Mouse - HIT421, Lectin Complement Pathway, Mouse - HIT422, Alternative Complement Pathway, Mouse The innate immune system is important in the first defense against foreign pathogens. A major component of this response is the...
| Keywords: | Complement Pathway |
| Application: | ELISA |
| Species reactivity: | mouse |
1,854.00€
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TCC, Rat, ELISA kit
Item number: HYC-HK106-01
Protein Function: Pore-forming component of the membrane attack complex (MAC), a multiprotein complex activated by the complement cascade, which inserts into a target cell membrane and forms a pore, leading to target cell membrane rupture and cell lysis (PubMed:9212048). The MAC is initiated by proteolytic cleavage...
| Keywords: | C9, Complement component C9 |
| Application: | ELISA |
| Species reactivity: | rat |
From 858.00€
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MASP-1/C1-INH complex, Human, ELISA kit
Item number: HYC-HK3001-01
Protein Function: Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to...
| Keywords: | MASP1, Serine protease 5, Complement factor MASP-3, Ra-reactive factor serine protease p100, Mannan-binding lectin serine... |
| Application: | ELISA |
| Species reactivity: | human |
From 929.00€
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FHR-4, Human, ELISA kit
Item number: HYC-HK3006-01
The FHR-4, human, ELISA kit is to be used for the in vitro quantitative determination of FHR-4 in serum and plasma samples.
| Keywords: | CFHR4, Complement factor H-related protein 4 |
| Application: | ELISA |
| Species reactivity: | human |
From 858.00€
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BPI, Human, ELISA kit
Item number: HYC-HK314-01
Protein Function: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria, this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial...
| Keywords: | BPI, CAP 57, Bactericidal permeability-increasing protein |
| Application: | ELISA |
| Species reactivity: | human |
From 715.00€
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LL-37, Human, ELISA kit
Item number: HYC-HK321-01
Protein Function: Antimicrobial protein that is an integral component of the innate immune system (PubMed:14978112, PubMed:16637646, PubMed:18818205, PubMed:22879591, PubMed:9736536). Binds to bacterial lipopolysaccharides (LPS) (PubMed:16637646, PubMed:18818205). Acts via neutrophil N-formyl peptide receptors to...
| Keywords: | CAMP, Cathelicidin antimicrobial peptide, 18 kDa cationic antimicrobial protein |
| Application: | ELISA |
| Species reactivity: | human |
From 858.00€
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MBL, Human, ELISA kit
Item number: HYC-HK323-01
Protein Function: Calcium-dependent lectin involved in innate immune defense (PubMed:35102342). Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early...
| Keywords: | MBL2, MBP1, Collectin-1, Mannose-binding lectin, Mannan-binding protein, Mannose-binding protein C |
| Application: | ELISA |
| Species reactivity: | human |
From 786.00€
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MASP-2, Human, ELISA kit
Item number: HYC-HK326-01
Protein Function: Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase [The Uniprot Consortium]
| Keywords: | MASP2, MBL-associated serine protease 2, Mannan-binding lectin serine protease 2, Mannose-binding protein-associated... |
| Application: | ELISA |
| Species reactivity: | human |
From 929.00€
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SAP, Human, ELISA kit
Item number: HYC-HK331-01
Protein Function: Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin [The Uniprot Consortium]
| Keywords: | APCS, Serum amyloid P-component, 9.5S alpha-1-glycoprotein |
| Application: | ELISA |
| Species reactivity: | human |
From 715.00€
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Properdin, Human, ELISA kit
Item number: HYC-HK334-01
Protein Function: A positive regulator of the alternate pathway (AP) of complement (PubMed:16301317, PubMed:20382442, PubMed:28264884, PubMed:9748277). It binds to and stabilizes the C3- and C5-convertase enzyme complexes (PubMed:16301317, PubMed:20382442, PubMed:28264884, PubMed:9748277). Inhibits CFI-CFH mediated...
| Keywords: | CFP, Properdin, Complement factor P |
| Application: | ELISA |
| Species reactivity: | human |
From 858.00€
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Pentraxin 3, Human, ELISA kit
Item number: HYC-HK347-01
Protein Function: Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility [The Uniprot Consortium]
| Keywords: | PTX3, Pentaxin-related protein PTX3, Pentraxin-related protein PTX3, Tumor necrosis factor alpha-induced protein 5, Tumor... |
| Application: | ELISA |
| Species reactivity: | human |
From 715.00€
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