PARPtrap(TM) Assay Kit for PARP1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
BPS-80584-1	96 rxns		-	-	3 - 15 business days*		3,179.00€
BPS-80584-2	384 rxns		-	-	3 - 15 business days*		4,307.00€

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The PARPtrap(TM) Assay Kit is designed to measure PARP1/DNA complex formation in a high... more

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Product information "PARPtrap(TM) Assay Kit for PARP1"

The PARPtrap(TM) Assay Kit is designed to measure PARP1/DNA complex formation in a high throughput screening assay using fluorescence polarization (FP). The PARPtrap(TM) Assay Kit comes in a convenient 96-well format, with purified PARP1 enzyme, fluorescent labeled nicked DNA, and PARPtrap(TM) assay buffer for 100 enzyme reactions. The key to the PARPtrap(TM) Assay Kit is the fluorescent labeled nicked DNA. Without the PAR reaction, PARP1 binds to the fluorescent labeled nicked DNA, resulting in the emission of highly polarized light. However, after autoribosylation of PARP1, the nicked DNA is dissociated from PARP1 and rotates freely, emitting less polarized light.

Keywords:	poly (ADP-ribose) polymerase 1, poly(ADP-ribosyl)transferase, ADPRT, PARP1,
Supplier:	BPS Bioscience
Supplier-Nr:	80584

Properties

Application:	Small molecule screening, drug discovery, HTS
Species reactivity:	human
Format:	Homog.

Database Information

KEGG ID :	K24070 \| Matching products
UniProt ID :	P09874 \| Matching products
Gene ID	GeneID 142 \| Matching products

Handling & Safety

Storage:	-80°C
Shipping:	-80°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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