Molecular Glue/PROTAC(R) Optimization Kit for CDK/Cyclin K-DDB1 Containing Complex

Molecular Glue/PROTAC(R) Optimization Kit for CDK/Cyclin K-DDB1 Containing Complex
Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-82588 384 rxns - -

3 - 15 business days*

2,091.00€
 
The Molecular Glue/PROTAC(R) Optimization Kit for CDK/Cyclin K-DDB1 Containing Complex is an... more
Product information "Molecular Glue/PROTAC(R) Optimization Kit for CDK/Cyclin K-DDB1 Containing Complex"
The Molecular Glue/PROTAC(R) Optimization Kit for CDK/Cyclin K-DDB1 Containing Complex is an AlphaLISA(R) assay designed for the testing and profiling of Molecular Glues (MG) and PROTACs targeting CDK12 (cyclin dependent kinase 12) or CDK13 kinases and any complex containing DDB1 (DNA damage binding protein 1). The kit comes with enough recombinant CDK12/Cyclin K complex, Cereblon/DDB1/CUL4A (culin 4A)/Rbx1 (RING-box protein 1) as a DDB1-containing complex, and optimized PROTAC(R) buffer. This kit also contains the control molecular glue (R)-CR8, and the dual CDK12-CDK13 inhibitor THZ531.
Keywords: XAP1, DDBa, XPCe, DDB1, XAP-1, XPE-BF, UV-DDB 1, DDB p127 subunit, XPE-binding factor, HBV X-associated protein 1, DNA damage-binding protein 1, DNA damage-binding protein a, UV-damaged DNA-binding factor, UV-damaged DNA-binding protein 1,
Supplier: BPS Bioscience
Supplier-Nr: 82588

Properties

Application: Molecular Glue/PROTAC identification/optimization
Species reactivity: human
Format: Homog.

Handling & Safety

Storage: -80°C
Shipping: -80°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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