Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used

Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay700190-96 | 96 wells | - |
6 - 10 business days* |
367.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
beta-Hydroxybutyrate (beta-HB, 3-hydroxybutyric acid) is a "ketone body" which is produced in the... more
Product information "beta-Hydroxybutyrate (Ketone Body) Colorimetric Assay Kit"
beta-Hydroxybutyrate (beta-HB, 3-hydroxybutyric acid) is a "ketone body" which is produced in the liver, mainly from the oxidation of fatty acids, and is exported to peripheral tissues for use as an energy source. The term 'ketone body' refers to three molecules, acetoacetate, beta-HB, and acetone. beta-HB and acetoacetate transport energy from the liver to the other tissues and acetone is generated by spontaneous decarboxylation of acetoacetate. The presence of ketosis may be normal or pathologic. Normally ketosis can indicate that lipid metabolism has been activated and the pathway of lipid degradation is intact. Normal ketosis is prevalent in many circumstances such as during fasting, after prolonged exercise or after a high fat diet. Pathological causes of ketosis include multiple organ failure, diabetes, childhood hypoglycemia, corticosteroid or growth hormone deficiency, intoxication with alcohol or salicylates and several inborn errors of metabolism. In acutely ill patients, these ketone bodies can accumulate in the body to cause ketoacidosis, which leads to the potentially life threatening condition known as metabolic acidosis. The presence and degree of ketosis can be determined by measuring blood levels of beta-HB. Ordinarily, beta-HB accounts for approximately 75% of the ketone bodies in serum. Measurement of beta-HB provides a reliable index of the level of ketoacidosis, including the detection of subclinical ketosis. In diabetics, beta-HB measurements (and blood glucose) can be used for the assessment of the severity of diabetic coma and is essential for the exclusion of hyperosmolar non-ketotic diabetic coma. The measurement of beta-HB is also used to monitor insulin requirements, based on existing hyperketonemia. beta-HB has more recently been evaluated for use in neurodegenerative diseases and inhibition of adipocyte lipolysis. Cayman's beta-HB (Ketone Body) Assay Kit provides a simple, reproducible, and sensitive tool for measuring beta-HB levels in plasma, serum, urine, cell lysates, or tissue homogenates. The method for beta-HB determination is based upon the oxidation of D-3-Hydroxybutyrate to acetoacetate by the enzyme 3-hydroxybutyrate dehydrogenase. Concomitant with this oxidation, the cofactor NAD+ is reduced to NADH. In the presence of diaphorase, NADH reacts with the colorimetric detector WST-1 to produce a formazan dye with an absorbance maximum at 445-455 nm. The absorbance of the dye is directly proportional to the beta-HB concentration.Synonyms: beta-HB, 3-Hydroxybutyric Acid.
Keywords: | 3-Hydroxybutyric Acid, beta-HB |
Supplier: | Cayman Chemical |
Supplier-Nr: | 700190 |
Properties
Application: | beta-HB measurement |
Format: | Homog. |
Database Information
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Signal Word: | Warning |
GHS Hazard Pictograms: |
![]() |
H Phrases: | H315, H319, H335 |
P Phrases: | P261, P264, P271, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed