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Item number: Cay701230-96
The COX (human) Inhibitor Screening Assay directly measures PGF2alpha by stannous chloride reduction of COX-derived PGH2 produced in the COX reaction. The prostanoid product is quantified via ELISA using an antiserum specific to PGF2a. This assay includes recombinant human COX-1 and COX-2 and is an excellent tool...
| Keywords: | Cyclooxygenase (human) Inhibitor Screening Assay Kit |
| Application: | Inhibitor screening |
| Species reactivity: | human |
667.00€
*
Item number: Cay760700-96
Lipoxygenases are members of a class of non-heme iron-containing dioxygenases that catalyze the addition of molecular oxygen to fatty acids containing a cis,cis-1,4-pentadiene system to give an unsaturated fatty acid hydroperoxide. In mammals, lipoxygenases carry out the first step in the arachidonic acid cascade....
| Keywords: | LO Inhibitor Screening Assay Kit |
| Application: | LO inhibitor screening |
498.00€
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Item number: BR-A05106.96
Protein function: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. [The UniProt Consortium]
| Keywords: | GHRL, MTLRP |
| Species reactivity: | human |
From 688.00€
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Item number: Cay600610-192
Cayman's Neutrophil Elastase Activity Assay kit employs a specific non-fluorescent elastase substrate, (Z-Ala-Ala-Ala-Ala)2Rh110, which is selectively cleaved by elastase to yield the highly fluorescent compound R110. Fluorescence can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525...
| Keywords: | HLE, ELA2, ELANE, Elastase-2, Medullasin, EC=3.4.21.37, PMN elastase, Neutrophil elastase, Human leukocyte elastase, Bone... |
| Application: | Neutrophile elastase detection |
| Species reactivity: | human |
686.00€
*
Item number: AG-45B-0004-KI01
Protein function: Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX By similarity. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization. [The UniProt...
| Keywords: | PN, OSF2, POSTN, OSF-2, Periostin, Osteoblast-specific factor 2 |
| Application: | ELISA |
| Species reactivity: | human |
627.00€
*
Item number: HYC-HIT422
The HIT422 measures the alternative pathway activity mediated via LPS. Complement deficiencies or other defects in the complement system can easily be screened by running an assay for each pathway in parallel or separately. The ELISA contains a positive control which can be used as control to ensure that the...
| Keywords: | AP, alternative pathway |
| Application: | ELISA |
| Species reactivity: | mouse |
929.00€
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Item number: HYC-HIT423
The HIT423 contains three Complement Pathway Assays: - HIT420, Classical Complement Pathway, Mouse - HIT421, Lectin Complement Pathway, Mouse - HIT422, Alternative Complement Pathway, Mouse The innate immune system is important in the first defense against foreign pathogens. A major component of this response is the...
| Keywords: | Complement Pathway |
| Application: | ELISA |
| Species reactivity: | mouse |
1,854.00€
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Item number: HYC-HK106-01
Protein Function: Pore-forming component of the membrane attack complex (MAC), a multiprotein complex activated by the complement cascade, which inserts into a target cell membrane and forms a pore, leading to target cell membrane rupture and cell lysis (PubMed:9212048). The MAC is initiated by proteolytic cleavage...
| Keywords: | C9, Complement component C9 |
| Application: | ELISA |
| Species reactivity: | rat |
From 858.00€
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Item number: HYC-HK3001-01
Protein Function: Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to...
| Keywords: | MASP1, Serine protease 5, Complement factor MASP-3, Ra-reactive factor serine protease p100, Mannan-binding lectin serine... |
| Application: | ELISA |
| Species reactivity: | human |
From 929.00€
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Item number: HYC-HK3006-01
The FHR-4, human, ELISA kit is to be used for the in vitro quantitative determination of FHR-4 in serum and plasma samples.
| Keywords: | CFHR4, Complement factor H-related protein 4 |
| Application: | ELISA |
| Species reactivity: | human |
From 858.00€
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Item number: HYC-HK314-01
Protein Function: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria, this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial...
| Keywords: | BPI, CAP 57, Bactericidal permeability-increasing protein |
| Application: | ELISA |
| Species reactivity: | human |
From 715.00€
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Item number: HYC-HIT413
The HIT413 contains three Complement Pathway Assays: - HIT410, Classical Complement Pathway, Rat - HIT411, Lectin Complement Pathway, Rat - HIT412, Alternative Complement Pathway, Rat The innate immune system is important in the first defense against foreign pathogens. A major component of this response is the...
| Keywords: | Complement Pathway |
| Application: | ELISA |
| Species reactivity: | rat |
1,854.00€
*