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Item number: ARG83674.1
Protein function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. {ECO:0000269, PubMed:11173916, ECO:0000269,...
| Keywords: | CD54, CD54, ICAM1, ICAM-1, ICAM-1, Major group rhinovirus receptor, Major group rhinovirus receptor, Intercellular... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83688.1
Protein function: Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. {ECO:0000269, PubMed:10583602}. [The UniProt Consortium]
| Keywords: | B7, B7, BB1, BB1, CD80, CD80, CD80, CD28LG, Activation B7-1 antigen, Activation B7-1 antigen, CTLA-4 counter-receptor... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83695.1
Protein function: Receptor for TNFSF8/CD30L (PubMed:8391931). May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa- B (PubMed:8999898). {ECO:0000269, PubMed:8391931, ECO:0000269, PubMed:8999898}. [The UniProt...
| Keywords: | Ki-1 antigen, Ki-1 antigen, CD30L receptor, CD30L receptor, CD30 {ECO:0000303|PubMed:7527901}, CD30... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83696.1
Protein function: Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state (PubMed:10611343, PubMed:15597323, PubMed:11320212). Preferentially recognizes and binds alpha-2,3- and more avidly alpha-2,6-linked...
| Keywords: | CD33, gp67, CD33, gp67, CD33, SIGLEC3, Siglec-3, Siglec-3, Myeloid cell surface antigen CD33, Myeloid cell surface antigen... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83697.1
Protein function: Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. [The UniProt Consortium]
| Keywords: | CD48, BCM1, CD48, CD48, TCT.1, TCT.1, SLAMF2, SLAMF2, CD48 antigen, CD48 antigen, BCM1 surface antigen, SLAM family member... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83709.1
Protein function: Abundant protease in the cytosolic granules of cytotoxic T- cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological synapse (PubMed:3257574, PubMed:3262682, PubMed:3263427, PubMed:32299851, PubMed:12819770). It cleaves after...
| Keywords: | CTLA3, Fragmentin-1, Fragmentin-1, HF {ECO:0000303|PubMed:3257574}, HF {ECO:0000303|PubMed:3257574}, H factor... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83718.1
Protein function: Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity. [The UniProt Consortium]
| Keywords: | CD134, CD134, TXGP1L, TNFRSF4, ACT35 antigen, ACT35 antigen, OX40L receptor, OX40L receptor, Tumor necrosis factor... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83720.1
Protein function: Forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta protein 42, a cleavage product of the amyloid-beta precursor protein APP, and mediates its uptake and degradation by microglia...
| Keywords: | TREM2, TREM-2, TREM-2, Triggering receptor expressed on monocytes 2, Triggering receptor expressed on monocytes 2,... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83724.1
Protein function: Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6,...
| Keywords: | Za11, Za11, IL-21, IL-21, Interleukin-21, Interleukin-21 |
| Application: | ELISA |
| Species reactivity: | mouse |
719.00€
*
Item number: ARG83732.1
Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and...
| Keywords: | CDF, CDF, IL-6, IL-6, IFNB2, BSF-2, BSF-2, IFN-beta-2, IFN-beta-2, Interferon beta-2, Interferon beta-2, Hybridoma growth... |
| Application: | ELISA |
| Species reactivity: | rat |
719.00€
*
Item number: ARG83665.96
Protein function: May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity. Component of the elastin-associated microfibrils (PubMed:8557636). {ECO:0000250, UniProtKB:Q9QZJ6, ECO:0000269, PubMed:8557636}. [The...
| Keywords: | MP25, MP25, MFAP5, MAGP2, MFAP-5, MAGP-2, MFAP-5, MAGP-2, Microfibrillar-associated protein 5, Microfibrillar-associated... |
| Application: | ELISA |
| Species reactivity: | human |
1,052.00€
*