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Item number: E-ESP-H0002.480
Protein function: Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation (PubMed:16914093, PubMed:8666937). Primarily signals through the JAK-STAT...
| Keywords: | IFNG, IFN-gamma, Interferon gamma, Immune interferon, Human IFN-gamma (Interferon Gamma) ELISPOT Kit |
| Application: | ELISPOT |
From 426.00€
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Item number: E-ESP-H0004.480
Protein function: Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity (PubMed:24120361). Signals via IL17RA-IL17RC heterodimeric receptor complex, triggering homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter. This...
| Keywords: | IL-17, CTLA8, IL17A, IL-17A, CTLA-8, Interleukin-17A, Cytotoxic T-lymphocyte-associated antigen 8, Human IL-17A... |
| Application: | ELISPOT |
From 426.00€
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Item number: E-ESP-H0005.480
Protein function: Potent pro-inflammatory cytokine (PubMed:10653850, PubMed:12794819, PubMed:28331908, PubMed:3920526). Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody...
| Keywords: | IL1F2, IL-1 beta, Catabolin, Interleukin-1 beta, Human IL-1beta (Interleukin 1beta) ELISPOT Kit |
| Application: | ELISPOT |
From 426.00€
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Item number: E-ESP-H0008.480
Protein function: Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils (PubMed:2653458, PubMed:9010276). Also acts on activated and resting B-cells to induce immunoglobulin production, growth, and...
| Keywords: | IL5, TRF, IL-5, Interleukin-5, T-cell replacing factor, B-cell differentiation factor I, Eosinophil differentiation... |
| Application: | ELISPOT |
From 426.00€
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Item number: E-ESP-H0009.480
Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and...
| Keywords: | CDF, IL-6, IFNB2, BSF-2, IFN-beta-2, Interleukin-6, Interferon beta-2, Hybridoma growth factor, CTL differentiation... |
| Application: | ELISPOT |
From 426.00€
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Item number: E-ESP-H0010.480
Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia,...
| Keywords: | TNF, TNFA, Human TNF-alpha (Tumor Necrosis Factor Alpha) ELISPOT Kit |
| Application: | ELISPOT |
From 426.00€
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Item number: E-ESP-M0001.480
Protein function: Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation (PubMed:11585387, PubMed:8456301). Primarily signals through the JAK-STAT...
| Keywords: | Ifng, IFN-gamma, Interferon gamma, Mouse IFN-gamma (Interferon Gamma) ELISPOT Kit |
| Application: | ELISPOT |
From 426.00€
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Item number: E-ESP-H0003.480
Protein function: Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and...
| Keywords: | CSIF, IL10, IL-10, Interleukin-10, Cytokine synthesis inhibitory factor, Human IL-10 (Interleukin 10) ELISPOT Kit |
| Application: | ELISPOT |
From 426.00€
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Item number: E-ESP-H0006.480
Protein function: Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance (PubMed:6438535). Binds to a receptor complex composed of either the high-affinity trimeric...
| Keywords: | IL2, IL-2, TCGF, Aldesleukin, Interleukin-2, T-cell growth factor, Human IL-2 (Interleukin 2) ELISPOT Kit |
| Application: | ELISPOT |
From 426.00€
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Item number: E-ESP-H0007.480
Protein function: Cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses (PubMed:1993171, PubMed:3016727). Induces the expression of class II MHC molecules on...
| Keywords: | IL4, IL-4, BSF-1, Pitrakinra, Binetrakin, Interleukin-4, B-cell stimulatory factor 1, Lymphocyte stimulatory factor 1,... |
| Application: | ELISPOT |
From 426.00€
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