Anti-Ig Lambda Light Chain (mouse), Rabbit Monoclonal (RM110)

Recombinant Antibody. This antibody reacts to the lambda light chain of mouse immunoglobulins. No cross reactivity with the kappa light chain, human IgG, rat IgG, or goat IgG. Applications: WB (nonreduced), IP, ICC, IHC, FACS, ELISA . Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Immunoglobulins are heterotetramers composed of 2 immunoglobulin heavy and 2 immunoglobulin light chains. The immunoglobulin light chain is the small polypeptide subunit of an antibody (immunoglobulin). The light chains can be categorized into kappa type or lambda type and both are used to construct the antigen binding F(ab) region of an antibody along with the variable region of the heavy chain. Kappa chains generally represent more than 90% of mouse Ig light chains. The ratio of kappa and lambda light chains can be used to determine disease status by immunohistochemistry or ELISA based assays.