Anti-Human IgG3, clone RM119

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R20189-100UG 100 µg - -

3 - 10 business days*

755.00€
 
1 mg/ml in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide. This recombinant Human IgG3... more
Product information "Anti-Human IgG3, clone RM119"
1 mg/ml in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide. This recombinant Human IgG3 antibody reacts to the heavy chain of hIgG3. No cross reactivity with IgG1, IgG2, IgG4, IgM, IgA, IgD, IgE, mouse/rat/goat IgG. Protein function: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins- secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). [The UniProt Consortium]
Keywords: Anti-HDC, Anti-Ig gamma-3 chain C region, Anti-Heavy chain disease protein, Anti-Immunoglobulin heavy constant gamma 3, Human IgG3 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: R20189

Properties

Application: ICC, IHC, ELISA
Antibody Type: Monoclonal
Clone: RM119
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Human IgG3
Format: Secondary Antibodies

Database Information

UniProt ID : P01860 | Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-Human IgG3, clone RM119"
Write a review
or to review a product.
Viewed