Human sST2 Antibody Pair Set

Human sST2 Antibody Pair Set
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-KAB-0189.1 1 set (50 µl +100 µg) -

10 - 15 business days*

607.00€
 
Matched antibody pair. Protein function: Receptor for interleukin-33 (IL-33) which plays crucial... more
Product information "Human sST2 Antibody Pair Set"
Matched antibody pair. Protein function: Receptor for interleukin-33 (IL-33) which plays crucial roles in innate and adaptive immunity, contributing to tissue homeostasis and responses to environmental stresses together with coreceptor IL1RAP (PubMed:35238669). Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function (PubMed:16286016) (Probable). Upon tissue injury, induces UCP2- dependent mitochondrial rewiring that attenuates the generation of reactive oxygen species and preserves the integrity of Krebs cycle required for persistent production of itaconate and subsequent GATA3- dependent differentiation of inflammation-resolving alternatively activated macrophages. [The UniProt Consortium]
Keywords: DER4, IL1RL1, Protein ST2, Interleukin-1 receptor-like 1, Human sST2 Antibody Pair Set
Supplier: Elabscience
Supplier-Nr: E-KAB-0189

Properties

Application: ELISA
Antibody Type: Mixed
Conjugate: No
Species reactivity: human

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: vT)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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