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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| E-KAB-0463.1 | 1 set (50µl & 100µg) | - | - |
10 - 15 business days* |
607.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Plays a critical role in induction and maintenance of immune tolerance to self... more
Product information "Human PD-L1 Antibody Pair Set"
Protein function: Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813410, PubMed:28813417, PubMed:31399419). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443, PubMed:28813410, PubMed:28813417, PubMed:36727298). Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (PubMed:10581077). Can also act as a transcription coactivator: in response to hypoxia, translocates into the nucleus via its interaction with phosphorylated STAT3 and promotes transcription of GSDMC, leading to pyroptosis (PubMed:32929201). [The UniProt Consortium]
| Keywords: | B7H1, PD-L1, CD274, B7-H1, hPD-L1, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1, Human PD-L1 Antibody Pair Set |
| Supplier: | Elabscience |
| Supplier-Nr: | E-KAB-0463 |
Properties
| Application: | ELISA |
| Conjugate: | No |
| Species reactivity: | human |
Database Information
| KEGG ID : | K06745 | Matching products |
| UniProt ID : | Q9NZQ7 | Matching products |
| Gene ID : | GeneID 29126 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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