Anti-Human G-CSF Antibody Pair

Product Description: CSF3, also known as granulocyte colony-stimulating factor (G-CSF), is a gene that encodes a cytokine that plays a crucial role in the production, differentiation, and function of granulocytes, a type of white blood cell that is part of the innate immune response. The CSF3 gene is located on chromosome 17 in humans and chromosome 11 in mice. The encoded cytokine stimulates the bone marrow to produce granulocytes and release them into the bloodstream. It also promotes the survival, proliferation, and function of mature neutrophils, a type of granulocyte. Diseases associated with the CSF3 gene include neutropenia, a condition characterized by a low number of neutrophils, and mucositis, inflammation of the mucous membranes. Pharmaceutical analogs of naturally occurring G-CSF, such as filgrastim and lenograstim, are commonly used to manage chemotherapy-induced neutropenia. In addition to its role in the hematopoietic system, G-CSF has also been shown to have neurotrophic effects, promoting neurogenesis and neuroplasticity in the central nervous system. Protein Function: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes [The Uniprot Consortium]