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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| E-KAB-0707.1 | 1 set (50 µl +100 µg) | - |
7 - 16 business days* |
1,093.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Matched antibody pair. Protein function: Plays an important role in the regulation of cell... more
Product information "Human FGF1 Antibody Pair Set"
Matched antibody pair. Protein function: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV:ITGB3. Its binding to integrin, subsequent ternary complex formation with integrin and FGFR1, and the recruitment of PTPN11 to the complex are essential for FGF1 signaling. Induces the phosphorylation and activation of FGFR1, FRS2, MAPK3/ERK1, MAPK1/ERK2 and AKT1 (PubMed:18441324, PubMed:20422052). Can induce angiogenesis (PubMed:23469107). [The UniProt Consortium]
| Keywords: | FGF1, ECGF, aFGF, FGFA, FGF-1, HBGF-1, Fibroblast growth factor 1, Endothelial cell growth factor, Heparin-binding growth factor 1, Acidic fibroblast growth factor, Human FGF1 Antibody Pair Set |
| Supplier: | Elabscience |
| Supplier-Nr: | E-KAB-0707 |
Properties
| Application: | ELISA |
| Antibody Type: | Mixed |
| Conjugate: | No |
| Species reactivity: | human |
Database Information
| KEGG ID : | K18496 | Matching products |
| UniProt ID : | P05230 | Matching products |
| Gene ID : | GeneID 2246 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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