Human DEFbeta2/DEFB2 Antibody Pair Set

Human DEFbeta2/DEFB2 Antibody Pair Set
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-KAB-0450.1 1 set (50µl & 100µg) - -

10 - 15 business days*

607.00€
 
Protein function: Exhibits antimicrobial activity against Gram-negative bacteria and... more
Product information "Human DEFbeta2/DEFB2 Antibody Pair Set"
Protein function: Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria, with highest activity against Gram-negative bacteria (PubMed:10837369, PubMed:9202117). Antimicrobial activity against P.aruginosa seems to be salt-sensitive and is reduced with high salt concentrations greater than 25 mM (PubMed:10837369). Also exhibits antimicrobial activity against the yeast C.albicans (PubMed:10837369, PubMed:30050988, PubMed:9202117). Permeabilizes C.albicans cell membranes via targeting plasma membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP2), thereby leading to cell fragmentation and cell death (PubMed:30050988). Acts as a ligand for C- C chemokine receptor CCR6 (PubMed:10521347, PubMed:20068036). Binds to CCR6 and induces chemotactic activity of CCR6-expressing cells, such as immature dendritic cells and memory T cells (PubMed:10521347, PubMed:20068036). [The UniProt Consortium]
Keywords: SAP1, BD-2, hBD-2, DEFB4A, DEFB4B, DEFB102, Beta-defensin 2, Defensin, beta 2, Defensin beta 4A, Skin-antimicrobial peptide 1, Human DEFbeta2/DEFB2 Antibody Pair Set
Supplier: Elabscience
Supplier-Nr: E-KAB-0450

Properties

Application: ELISA
Conjugate: No
Species reactivity: human

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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