Human BCAM Antibody Pair Set

Human BCAM Antibody Pair Set
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-KAB-0697.1 1 set (50 µl +100 µg) -

7 - 16 business days*

607.00€
 
Matched antibody pair. Protein function: Transmembrane glycoprotein that functions as both a... more
Product information "Human BCAM Antibody Pair Set"
Matched antibody pair. Protein function: Transmembrane glycoprotein that functions as both a receptor and an adhesion molecule playing a crucial role in cell adhesion, motility, migration and invasion (PubMed:9616226, PubMed:31413112). Extracellular domain enables binding to extracellular matrix proteins, such as laminin, integrin and other ligands while its intracellular domain interacts with cytoskeletal proteins like hemoglobin, facilitating cell signal transduction (PubMed:17158232). Serves as a receptor for laminin alpha-5/LAMA5 to promote cell adhesion (PubMed:15975931). Mechanistically, JAK2 induces BCAM phosphorylation and activates its adhesion to laminin by stimulating a Rap1/AKT signaling pathway in the absence of EPOR (PubMed:23160466). [The UniProt Consortium]
Keywords: LU, BCAM, CD239, F8/G253 antigen, Lutheran antigen, Auberger B antigen, Basal cell adhesion molecule, B-CAM cell surface glycoprotein, Lutheran blood group glycoprotein, Human BCAM Antibody Pair Set
Supplier: Elabscience
Supplier-Nr: E-KAB-0697

Properties

Application: ELISA
Antibody Type: Mixed
Conjugate: No
Species reactivity: human

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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