Anti-Human SERPINB8 Antibody Pair

Product Description: Serpin family B member 8 (SERPINB8) is an intracellular serine protease inhibitor that plays a crucial role in regulating protease activity within various physiological processes, particularly in epithelial tissues like the skin. The protein, encoded by a gene located on chromosome 18q21.3, consists of approximately 376 amino acids with a molecular weight of around 42 kDa and features a typical serpin structure with three beta-sheets and multiple alpha-helices. SERPINB8 is involved in inhibiting serine proteases, protecting tissues from protease-mediated damage, and is linked to several skin conditions, including peeling skin syndrome type B and inflammatory skin diseases like psoriasis and eczema. Its function is essential for maintaining tissue integrity and regulating inflammatory responses. Protein Function: Has an important role in epithelial desmosome-mediated cell-cell adhesion [The Uniprot Consortium]