Anti-Human MAST4 Antibody Pair

Product Description: Microtubule-associated serine/threonine-protein kinase 4 (MAST4) is a serine/threonine kinase that plays a significant role in various cellular processes, particularly in the regulation of cell signaling pathways involved in differentiation and development. MAST4 is primarily associated with microtubules and is implicated in the modulation of cytoskeletal dynamics, influencing cell shape and motility. Research has shown that MAST4 is essential for the differentiation of mesenchymal stem cells (MSCs) into chondrocytes and osteoblasts by mediating signaling pathways such as TGF-beta and Wnt. Dysregulation of MAST4 expression has been linked to diseases such as osteoarthritis and osteoporosis, where its altered activity can disrupt normal bone and cartilage formation. Additionally, MAST4's involvement in cellular signaling suggests potential implications in cancer progression, where it may affect tumor cell behavior.