Anti-Human FGF20 Antibody Pair

Product Description: Fibroblast growth factor 20 (FGF20) is a member of the FGF family, which are cell signaling proteins involved in diverse biological processes such as cellular proliferation, survival, migration, and differentiation through pathways like RAS/MAP kinase, PI3 kinase/AKT, and PLCgamma. FGFs, including FGF20, interact with specific fibroblast growth factor receptors (FGFRs) on the cell surface, forming a ternary complex with heparan sulfate chains to initiate downstream signaling. These proteins are critical for tissue regeneration and development, with their biological stability and half-life being important for therapeutic applications. FGF20, like other FGFs, plays a significant role in tissue repair and homeostasis, influencing processes such as bone formation and neural development. In terms of disease, dysregulation of FGF signaling, including FGF20, has been implicated in various pathological conditions, such as impaired tissue regeneration and potentially in cancer progression, due to its effects on cell proliferation and migration. Protein Function: Neurotrophic factor that regulates central nervous development and function [The Uniprot Consortium]