Anti-Human EVPLL Antibody Pair

Product Description: Envoplakin like (EVPLL) is encoded by the EVPLL gene located on human chromosome 17. It is a member of the plakin family and shares structural similarities with envoplakin. EVPLL plays a role in structural molecule activity, intermediate filament organization, and wound healing. The protein contains spectrin repeats, which are involved in cytoskeletal structure. EVPLL is expressed in various tissues and is conserved across different species. In terms of disease associations, EVPLL has been found to be overexpressed in patients with better survival outcomes in Head and Neck Squamous Cell Carcinoma (HNSCC). Additionally, research suggests that EVPLL may contribute to neurodegeneration in Alzheimer's disease due to its proximity to AD-associated piRNA DQ586113. Other diseases linked to EVPLL include Three M Syndrome 1 and Autism Spectrum Disorder.