Anti-Human CA5B Antibody Pair

Product Description: Carbonic anhydrase 5B (CA5B) is a mitochondrial enzyme that catalyzes the reversible hydration of carbon dioxide to bicarbonate and protons, playing a crucial role in maintaining acid-base balance and facilitating respiratory gas exchange. It is characterized by its zinc-binding site, which is essential for its enzymatic activity, and its localization in the mitochondria, where it participates in various metabolic processes. Dysregulation or mutations in the CA5B gene have been associated with several diseases, particularly renal tubular acidosis, a condition characterized by the inability of the kidneys to excrete acids into the urine, leading to a systemic acid-base imbalance. Additionally, alterations in CA5B activity may contribute to metabolic disorders and conditions related to impaired mitochondrial function. Protein Function: Mitochondrial carbonic anhydrase that catalyzes the reversible conversion of carbon dioxide to bicarbonate/HCO3 [The Uniprot Consortium]