Anti-Human C1QTNF9 Antibody Pair

Product Description: C1q and TNF-related protein 9 (C1QTNF9), also known as CTRP9, is a secreted glycoprotein predominantly expressed in adipose tissue and cardiac endothelial cells. It plays a significant role in various physiological processes, including glucose and lipid metabolism, vasodilation, and inflammation regulation. CTRP9 activates key signaling pathways such as AMPK, AKT, and MAPK, which are crucial for maintaining metabolic homeostasis. Dysregulation of C1QTNF9 expression is associated with several diseases, particularly metabolic disorders like diabetes mellitus and diabetic cardiomyopathy. Studies indicate that CTRP9 has protective effects against inflammation and oxidative stress, enhancing insulin sensitivity and reducing cardiac dysfunction in diabetic models. Protein Function: Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways [The Uniprot Consortium]