Anti-Human C19orf53 Antibody Pair

Product Description: Chromosome 19 open reading frame 53 (C19orf53) known as Leydig cell tumor 10 kDa protein homolog. It belongs to the UPF0390 family and may have a potential role in hypercalcemia of malignancy. C19orf53 exhibits chaperone-like properties and has been identified as a "heat-resistant obscure" or "Hero" protein, displaying resilience and the ability to suppress pathological protein aggregation. It plays a role in mediating excessive cell proliferation, leading to metabolic imbalance and increased oxidative stress in response to toxins. Recent studies have associated C19orf53 with ischemic stroke risk, with genetic variations in the gene potentially influencing disease susceptibility. Additionally, C19orf53 has been implicated in various biological pathways, including rRNA biogenesis, ovarian cancer, and Zika virus replication. Protein Function: May have a potential role in hypercalcemia of malignancy [The Uniprot Consortium]