Products from NewEast Biosciences
NewEast Biosciences, headquartered in King of Prussia, Pennsylvania, produces antibodies, proteins and assay kits with a strong focus on G-protein research. You also find mutation-specific antibodies as well as cAMP and cGMP kits with extraordinary specificity due to the use of monoclonal antibodies.
More information at: www.neweastbio.com
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Anti-BRCA2 (352-643)
Item number: NB-26364-1
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts...
| Keywords: | Anti-FACD, Anti-BRCA2, Anti-Fanconi anemia group D1 protein, Anti-Breast cancer type 2 susceptibility protein |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
384.00€
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Anti-BRCA2 (1475-1748)
Item number: NB-26364-2
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts...
| Keywords: | Anti-FACD, Anti-BRCA2, Anti-Fanconi anemia group D1 protein, Anti-Breast cancer type 2 susceptibility protein |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
384.00€
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Anti-BRCA2 (2793-3030)
Item number: NB-26364-4
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts...
| Keywords: | Anti-FACD, Anti-BRCA2, Anti-Fanconi anemia group D1 protein, Anti-Breast cancer type 2 susceptibility protein |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-ERBB2 (D769H)
Item number: NB-26381
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex,...
| Keywords: | Anti-HER2, Anti-CD340, Anti-ERBB2, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene... |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-FGFR1 N-terminal
Item number: NB-26386
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation...
| Keywords: | Anti-BFGFR, Anti-FLT-2, Anti-FGFR1, Anti-N-sam, Anti-CD331, Anti-FGFR-1, Anti-bFGF-R-1, Anti-Proto-oncogene c-Fgr,... |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-IDH1 (R132P)
Item number: NB-26406
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Catalytic activity of cytoplasmic Isocitrate dehydrogenase [NADP] (EC:1.1.1.42): Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.
| Keywords: | Anti-IDP, Anti-IDH, Anti-PICD, Anti-IDH1, EC=1.1.1.42, Anti-NADP(+)-specific ICDH, Anti-Oxalosuccinate decarboxylase,... |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-SMAD4 (D351H)
Item number: NB-26418
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4...
| Keywords: | Anti-DPC4, Anti-SMAD4, Anti-Smad4, Anti-hSMAD4, Anti-SMAD 4, Anti-MAD homolog 4, Anti-SMAD family member 4, Anti-Mothers... |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-SMAD4 (R361S)
Item number: NB-26423
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4...
| Keywords: | Anti-DPC4, Anti-SMAD4, Anti-Smad4, Anti-hSMAD4, Anti-SMAD 4, Anti-MAD homolog 4, Anti-SMAD family member 4, Anti-Mothers... |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-SMO (A68V)
Item number: NB-26425
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to...
| Keywords: | Anti-SMO, Anti-SMOH, Anti-Protein Gx, Anti-Smoothened homolog, mutation-specific (Ala68Val) |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-NOTCH1 (M2011R)
Item number: NB-26444
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it...
| Keywords: | Anti-TAN1, Anti-NOTCH1, mutation-specific (Met2011Arg) |
| Application: | ELISA, WB, IHC, IF |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-SMAD4
Item number: NB-26453
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4...
| Keywords: | Anti-DPC4, Anti-SMAD4, Anti-Smad4, Anti-hSMAD4, Anti-SMAD 4, Anti-MAD homolog 4, Anti-SMAD family member 4, Anti-Mothers... |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
384.00€
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Anti-Ras (K117N)
Item number: NB-26468
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting...
| Keywords: | Anti-KRAS, Anti-KRAS2, mutation-specific (Lys117Asn) |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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