Products from NewEast Biosciences
NewEast Biosciences, headquartered in King of Prussia, Pennsylvania, produces antibodies, proteins and assay kits with a strong focus on G-protein research. You also find mutation-specific antibodies as well as cAMP and cGMP kits with extraordinary specificity due to the use of monoclonal antibodies.
More information at: www.neweastbio.com
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Anti-GRB7
Item number: NB-26133
Concentration: 0.5 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3,...
| Keywords: | Anti-B47, Anti-GRB7, Anti-GRB7 adapter protein, Anti-Growth factor receptor-bound protein 7, Anti-Epidermal growth factor... |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
384.00€
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Anti-AKT1 (E49K)
Item number: NB-26137
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival,...
| Keywords: | Anti-PKB, Anti-AKT1, Anti-PKB alpha, EC=2.7.11.1, Anti-RAC-PK-alpha, Anti-Protein kinase B, Anti-Proto-oncogene c-Akt,... |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-RET (C634Y)
Item number: NB-26146
Concentration: 0.5 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell...
| Keywords: | Anti-RET, Anti-CDHF12, EC=2.7.10.1, mutation-specific (Cys634Tyr) |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-IDH1 (R132S)
Item number: NB-26160
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Catalytic activity of cytoplasmic Isocitrate dehydrogenase [NADP] (EC:1.1.1.42): Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.
| Keywords: | Anti-IDP, Anti-IDH, Anti-PICD, Anti-IDH1, EC=1.1.1.42, Anti-NADP(+)-specific ICDH, Anti-Oxalosuccinate decarboxylase,... |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-CTNNB1 (S37F)
Item number: NB-26168
Concentration: 1 mg/ml Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and...
| Keywords: | Anti-CTNNB, Anti-CTNNB1, Anti-Beta-catenin, Anti-Catenin beta-1, mutation-specific (Ser37Phe) |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-beta-catenin (G38D)
Item number: NB-26169
Concentration: 1 mg/ml Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and...
| Keywords: | Anti-CTNNB, Anti-CTNNB1, Anti-Beta-catenin, Anti-Catenin beta-1, mutation-specific (Gly38Asp) |
| Application: | ELISA, WB, IHC, IF |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-Ras (G13A)
Item number: NB-26191
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting...
| Keywords: | Anti-KRAS, Anti-KRAS2, mutation-specific (Gly13Ala) |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-Ras (Q61H)
Item number: NB-26195
Concentration: 2 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting...
| Keywords: | Anti-KRAS, Anti-KRAS2, mutation-specific (Gln61His) |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-B-Raf (G469E)
Item number: NB-26196
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1,...
| Keywords: | Anti-p94, Anti-BRAF, Anti-BRAF1, EC=2.7.11.1, Anti-Proto-oncogene B-Raf, Anti-Serine/threonine-protein kinase B-raf,... |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-B-Raf (V600A)
Item number: NB-26199
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1,...
| Keywords: | Anti-p94, Anti-BRAF, Anti-BRAF1, EC=2.7.11.1, Anti-Proto-oncogene B-Raf, Anti-Serine/threonine-protein kinase B-raf,... |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-PIK3CA (E545G)
Item number: NB-26208
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4- phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5- bisphosphate) to...
| Keywords: | Anti-PIK3CA, Anti-p110alpha, Anti-PI3Kalpha, Anti-PI3K-alpha, Anti-PI3-kinase subunit alpha, Anti-PtdIns-3-kinase subunit... |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-PIK3CA (E542Q)
Item number: NB-26210
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4- phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5- bisphosphate) to...
| Keywords: | Anti-PIK3CA, Anti-p110alpha, Anti-PI3Kalpha, Anti-PI3K-alpha, Anti-PI3-kinase subunit alpha, Anti-PtdIns-3-kinase subunit... |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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