Products from NewEast Biosciences
NewEast Biosciences, headquartered in King of Prussia, Pennsylvania, produces antibodies, proteins and assay kits with a strong focus on G-protein research. You also find mutation-specific antibodies as well as cAMP and cGMP kits with extraordinary specificity due to the use of monoclonal antibodies.
More information at: www.neweastbio.com
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Anti-CTNNB1 (T41I), monoclonal
Item number: NB-26306
Concentration: 2 mg/ml. PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Recognizes T41I mutant, but not wild-type CTNNB1 of vertebrates. Protein function: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B...
| Keywords: | Anti-CTNNB, Anti-CTNNB1, Anti-Beta-catenin, Anti-Catenin beta-1 |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | human |
746.00€
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Anti-IDH2 (R172G)
Item number: NB-26321
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex. [The UniProt Consortium]
| Keywords: | Anti-IDP, Anti-IDH, Anti-IDH2, Anti-ICD-M, EC=1.1.1.42, Anti-NADP(+)-specific ICDH, Anti-Oxalosuccinate decarboxylase,... |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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Anti-SMAD4 (R361H)
Item number: NB-26422
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4...
| Keywords: | Anti-DPC4, Anti-SMAD4, Anti-Smad4, Anti-hSMAD4, Anti-SMAD 4, Anti-MAD homolog 4, Anti-SMAD family member 4, Anti-Mothers... |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
384.00€
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Rac Activation Assay Kit
Item number: NB-80501
Configuration-specific monoclonal anti-Rac-GTP antibody based. This monoclonal antibody specifically recognizes Rac-GTP, but not Rac-GDP. Providing shorter experimental time. Providing reliable results with consistent reproducibility than other Rac activation assay kits. Could be used to monitor the activation of...
| Keywords: | RAC1, MIG5, TC25, p21-Rac1, Ras-like protein TC25, Cell migration-inducing gene 5 protein, Ras-related C3 botulinum toxin... |
| Application: | IP/WB G-Protein Activation assay |
| Species reactivity: | vertebrates |
1,080.00€
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G.alpha.z Activation Assay Kit
Item number: NB-81001
Configuration-specific monoclonal antibody that recognizes G.alpha.z-GTP, but not G.alpha.z-GDP. The only available G.alpha.z activation assay kit directly measures the level of G.alpha.z-GTP. Providing reliable results with consistent reproducibility than other G.alpha.z activation assay kits based on certain...
| Keywords: | GNAZ, Gz-alpha, G(x) alpha chain, Guanine nucleotide-binding protein G(z) subunit alpha |
| Application: | IP/WB G-Protein Activation assay |
| Species reactivity: | vertebrates |
1,080.00€
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Arf6 Activation Assay Kit
Item number: NB-82401
Configuration-specific monoclonal antibody that recognizes Arf6-GTP, but not Arf6-GDP. The only available Arf6 activation assay kit directly measures the level of Arf6-GTP. Providing shorter experimental time. Could be used to monitor the activation of Arf6 in cells and in tissues by immunohistochemistry. Protein...
| Keywords: | ARF6, ADP-ribosylation factor 6 |
| Application: | IP/WB G-Protein Activation assay |
| Species reactivity: | vertebrates |
1,080.00€
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Rab4A Activation Assay Kit
Item number: NB-82701
Configuration-specific monoclonal antibody that recognizes Rab4A-GTP, but not Rab4A-GDP. The only available Rab4A activation assay kit directly measures the level of Rab4A-GTP. Providing shorter experimental time. Could be used to monitor the activation of Rab4A in cells and in tissues by immunohistochemistry....
| Keywords: | RAB4, RAB4A, Ras-related protein Rab-4A |
| Application: | IP/WB G-Protein Activation assay |
| Species reactivity: | vertebrates |
1,080.00€
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Anti-AKT1
Item number: NB-21274
Concentration: 0.2 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell...
| Keywords: | Anti-PKB, Anti-AKT1, Anti-PKB alpha, EC=2.7.11.1, Anti-RAC-PK-alpha, Anti-Protein kinase B, Anti-Proto-oncogene c-Akt,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | vertebrates |
355.00€
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Anti-ATM
Item number: NB-21276
Concentration: 0.2 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting...
| Keywords: | Anti-ATM, EC=2.7.11.1, Anti-A-T mutated, Anti-Serine-protein kinase ATM, Anti-Ataxia telangiectasia mutated |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | vertebrates |
355.00€
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Anti-ALK (R1275Q)
Item number: NB-21280
Concentration: 0.5 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Protein function: Neuronal orphan receptor tyrosine kinase that is essentially and transiently expressed in specific regions of the central and peripheral nervous systems and plays an important role in the genesis...
| Keywords: | Anti-ALK, Anti-CD246, EC=2.7.10.1, Anti-Anaplastic lymphoma kinase, Anti-ALK tyrosine kinase receptor, mutation-specific... |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
355.00€
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Anti-EYA2, monoclonal
Item number: NB-26052
Concentration: 1mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. EYA2 may be involved in development of the eye. It promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase...
| Keywords: | Anti-EYA2, Anti-EAB1, EC=3.1.3.48, Anti-Eyes absent homolog 2 |
| Application: | ELISA, WB, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
384.00€
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Anti-EGFR (L861Q), monoclonal
Item number: NB-26077
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major...
| Keywords: | Anti-EGFR, Anti-ERBB, EC=2.7.10.1, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor... |
| Application: | ELISA, WB, IF, IHC |
| Host: | Mouse |
| Species reactivity: | vertebrates |
746.00€
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