Products from NewEast Biosciences
NewEast Biosciences, headquartered in King of Prussia, Pennsylvania, produces antibodies, proteins and assay kits with a strong focus on G-protein research. You also find mutation-specific antibodies as well as cAMP and cGMP kits with extraordinary specificity due to the use of monoclonal antibodies.
More information at: www.neweastbio.com
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![Cdc42 (Cell division cycle 42, G25K, CDC42Hs), human, recombinant full length, His6-tag [E. coli]](https://www.biomol.com/media/image/e8/11/95/NB-10107_200x200.jpg "Cdc42 (Cell division cycle 42, G25K, CDC42Hs), human, recombinant full length, His6-tag [E. coli]")
Cdc42 (Cell division cycle 42, G25K, CDC42Hs), human,...
Item number: NB-10107
Small GTPases are a super-family of cellular signaling regulators. Cdc42 belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Cdc42, and the hydrolysis of GTP to GDP renders it inactive. GTP hydrolysis is aided by GTPase...
| Keywords: | CDC42, G25K GTP-binding protein, Cell division control protein 42 homolog |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 21 kD |
384.00€
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![Arf1 delta17 mutant (ADP-ribosylation factor 1), human, recombinant, His6-tag [E. coli]](https://www.biomol.com/media/image/2d/95/40/NB-10122_200x200.jpg "Arf1 delta17 mutant (ADP-ribosylation factor 1), human, recombinant, His6-tag [E. coli]")
Arf1 delta17 mutant (ADP-ribosylation factor 1), human,...
Item number: NB-10122
Arf1 is a member of the ARF super-family. ARF genes encode small GTPases that increase the ADP-ribosyltransferase activity of cholera toxin and are critical for vesicular trafficking as activators of phospholipase D. Arf1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport.
| Keywords: | ARF1, ADP-ribosylation factor 1 |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 21 kD |
540.00€
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Rab11 (Rab-protein 11, CG5771, DmRab11, Drab11, Rab-r11,...
Item number: NB-10126
Rab11 is a small GTP-binding proteins of the Rab family, such as Rab11A, play essential roles in vesicle and granule targeting. Rab11 is also a GTPase that regulates endosomal trafficking to apical plasma membrane domains in polarized epithelial cells.
| Keywords: | YL8, RAB11, Rab-11, RAB11A, Ras-related protein Rab-11A |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 18 kD |
540.00€
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G.alpha.i2 Q205L mutant (Guanine nucleotide binding...
Item number: NB-10147
Heterotrimeric G proteins are critical cellular signal transducers. G.alpha.i represents one sub-family of G proteins that could mediate the inhibition of adenylyl cyclases. Other biochemical and physiological functions of G.alpha.i proteins are being explored.
| Keywords: | GNAI1, Adenylate cyclase-inhibiting G alpha protein, Guanine nucleotide-binding protein G(i) subunit alpha-1 |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 40 kD |
529.00€
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RalB (v-ral simian leukemia viral oncogene homolog B),...
Item number: NB-10169
The Ras-like small G proteins, RalA/B, are important components of Ras signaling pathways, implicated in the initiation and maintenance of tumorigenic transformation, as well as vesicle transport, apoptosis, transcription, cell migration, and cell proliferation.
| Keywords: | RAL, RALA, Ras-related protein Ral-A |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 23 kD |
369.00€
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Anti-Rab17
Item number: NB-20149
Protein function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream...
| Keywords: | Anti-RAB17, Anti-Ras-related protein Rab-17, Anti Rab17 Rabbit Polyclonal Antibody |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human |
355.00€
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Anti-Rab13
Item number: NB-21406
Protein function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream...
| Keywords: | Anti-GIG4, Anti-RAB13, Anti-Ras-related protein Rab-13, Anti-Cell growth-inhibiting gene 4 protein, Anti Rab13 Rabbit... |
| Application: | ELISA, WB, IHC, IP |
| Host: | Rabbit |
| Species reactivity: | human |
355.00€
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Anti-CTNNB1 (S45P)
Item number: NB-26037
Protein function: Key downstream component of the canonical Wnt signaling pathway (PubMed:17524503, PubMed:18077326, PubMed:18086858, PubMed:18957423, PubMed:21262353, PubMed:22155184, PubMed:22647378, PubMed:22699938). In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes...
| Keywords: | Anti-CTNNB (Ser45Pro), Anti-CTNNB1, Anti-Beta-catenin, Anti-Catenin beta-1, Anti CTNNB1(S45P) Mouse Monoclonal Antibody,... |
| Application: | ELISA, IF, IHC |
| Host: | Mouse |
| Species reactivity: | human |
746.00€
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Anti-PTEN (R130G)
Item number: NB-26312
Protein function: Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate,...
| Keywords: | Anti-PTEN (Arg130Gly), Anti-MMAC1, Anti-Phosphatase and tensin homolog, Anti-Mutated in multiple advanced cancers 1,... |
| Application: | ELISA, WB |
| Host: | Mouse |
| Species reactivity: | human |
746.00€
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Anti-PTEN (R159S)
Item number: NB-26313
Protein function: Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate,...
| Keywords: | Anti-PTEN (Arg159Ser), Anti-MMAC1, Anti-Phosphatase and tensin homolog, Anti-Mutated in multiple advanced cancers 1,... |
| Application: | ELISA, WB |
| Host: | Mouse |
| Species reactivity: | human |
746.00€
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Tri-Color Prestained Protein
Item number: NB-22301
Tri-Color Prestained Protein Markers are a mixture of recombinant proteins ranging from 10 kD to 250 kD. Red and green bands at 25 kD and 70 kD and provide easy references for molecular weight identification. The molecular weights of the prestained markers are confirmed in Tris-Glycine SDS-PAGE system with an...
| Keywords: | Three colored prestained protein molecular weight marker |
| Species reactivity: | broad |
| MW: | 10-250 kD |
187.00€
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Human GPR75 Protein, hFc Tag
Item number: NB-11497
Recombinant human GPR75 Protein with C-terminal Human Fc tag. GPR75(Met1-Thr46) hFc(Glu99-Ala330). GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[supplied by OMIM, Jul 2002]
| Keywords: | G protein-coupled receptor 75, Probable G-protein coupled receptor 75, GPRchr2, WI31133 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 31 kD |
1,054.00€
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