Products from NewEast Biosciences
NewEast Biosciences, headquartered in King of Prussia, Pennsylvania, produces antibodies, proteins and assay kits with a strong focus on G-protein research. You also find mutation-specific antibodies as well as cAMP and cGMP kits with extraordinary specificity due to the use of monoclonal antibodies.
More information at: www.neweastbio.com
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Fascin1 (Fascin homolog 1, actin-bundling protein, FSCN1,...
Item number: NB-10150
Fascin is an ~58 kDa monomeric actin filament bundling protein. It is required to maximally cross-link the actin filaments into straight, compact, and rigid bundles, and contributes to the formation of filopodia that are critical for cell migration. Elevated levels of fascin have been found in metastatic tumors and...
| Keywords: | p55, FAN1, FSCN1, Fascin, Singed-like protein, 55 kDa actin-bundling protein |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 55 kD |
From 369.00€
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![Arl3 (ADP-ribosylation factor-like 3, ARFL3), human, recombinant full length, His6-tag [E. coli]](https://www.biomol.com/media/image/0a/b6/51/NB-10152_200x200.jpg "Arl3 (ADP-ribosylation factor-like 3, ARFL3), human, recombinant full length, His6-tag [E. coli]")
Arl3 (ADP-ribosylation factor-like 3, ARFL3), human,...
Item number: NB-10152
Arl3 belongs to the member of the Arf family of regulatory GTPases, within the Ras superfamily of GTPases. Arl3 is also a member of the ADP-ribosylation factor family of GTP-binding proteins. Arl3 binds guanine nucleotides but lacks ADP-ribosylation factor activity.
| Keywords: | ARL3, ARFL3, ADP-ribosylation factor-like protein 3 |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 20 kD |
369.00€
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Arl1 Q71L mutant (ADP-ribosylation factor-like 1, ARFL1),...
Item number: NB-10156
Arl1 is a member of the Arf family of regulatory GTPases, within the Ras superfamily of GTPases (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform.
| Keywords: | ARL1, ADP-ribosylation factor-like protein 1 |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 20 kD |
369.00€
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![CST3 (Cystatin C, Cystatin 3, CYSC), human, recombinant full length, His6-tag [E. coli]](https://www.biomol.com/media/image/bd/b5/e1/NB-10157_200x200.jpg "CST3 (Cystatin C, Cystatin 3, CYSC), human, recombinant full length, His6-tag [E. coli]")
CST3 (Cystatin C, Cystatin 3, CYSC), human, recombinant...
Item number: NB-10157
Cystatin C, which belongs to the type 2 cystatin gene family, is a potent inhibitor of lysosomal proteinases. It regulates the activity of cathepsin S, a protease with central regulatory functions in retinal pigment epithelial (RPE) cells
| Keywords: | CST3, Cystatin-3, Cystatin-C, Gamma-trace, Post-gamma-globulin, Neuroendocrine basic polypeptide |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 16 kD |
369.00€
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Ras Q61L mutant (Resistance to audiogenic seizures, Asr),...
Item number: NB-10111
Small GTPases are a super-family of cellular signaling regulators. Ras belongs to the Ras sub-family of GTPases that regulate cell proliferation, cell motility, and gene transcription. GTP binding increases the activity of Ras, and the hydrolysis of GTP to GDP renders it inactive. GTP hydrolysis is aided by GTPase...
| Keywords: | KRAS, KRAS2 |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 21 kD |
397.00€
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Rab5 (Member RAS oncogene family, RAB5A) (16-184), human,...
Item number: NB-10116
Rab5, consists of three isoforms, Rab5A, Rab5B, and Rab5C, is a small GTPase that is localized to early endosomes. It regulates the fusion between endocytic vesicles and early endosomes, as well as the homotypic fusion between early endosomes. Amino Acid Sequence (16-184): NKICQFKLVL LGESAVGKSS LVLRFVKGQF HEFQESTIGA...
| Keywords: | RAB5, RAB5A, Ras-related protein Rab-5A |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 17 kD |
384.00€
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Rap1B (Member of RAS oncogene family, K-REV, RAL1B),...
Item number: NB-10120
Small GTPases are a super-family of cellular signaling regulators. Rap family members (Rap1A, Rap1B, Rap2A, Rap2B, and Rap2C) are Ras-like GTPases that regulate cell proliferation, differentiation, apoptosis and adhesion mechanisms. Rap1 (Ras-proximate-1) regulates apoptosis through interaction with two MAP3K...
| Keywords: | RAP1B, Ras-related protein Rap-1b, GTP-binding protein smg p21B |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 21 kD |
540.00€
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![Arf6 (ADP-ribosylation factor 6), human recombinant, His6-tag [E. coli]](https://www.biomol.com/media/image/4e/7d/12/NB-10124_200x200.jpg "Arf6 (ADP-ribosylation factor 6), human recombinant, His6-tag [E. coli]")
Arf6 (ADP-ribosylation factor 6), human recombinant,...
Item number: NB-10124
Arf6 is a member of the ARF super-family. ARF genes encode small GTPases that increase the ADP-ribosyltransferase activity of cholera toxin and are critical for vesicular trafficking as activators of phospholipase D. Arf6 regulates membrane trafficking and the actin cytoskeketon at the plasma membrane and functions...
| Keywords: | ARF6, ADP-ribosylation factor 6 |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 17 kD |
384.00€
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![Arf6 delta12 Q67L mutant (ADP-ribosylation factor 6), human, recombinant, His6-tag [E. coli]](https://www.biomol.com/media/image/73/4d/cd/NB-10125_200x200.jpg "Arf6 delta12 Q67L mutant (ADP-ribosylation factor 6), human, recombinant, His6-tag [E. coli]")
Arf6 delta12 Q67L mutant (ADP-ribosylation factor 6),...
Item number: NB-10125
Arf6 is a member of the ARF super-family. ARF genes encode small GTPases that increase the ADP-ribosyltransferase activity of cholera toxin and are critical for vesicular trafficking as activators of phospholipase D. Arf6 regulates membrane trafficking and the actin cytoskeketon at the plasma membrane and functions...
| Keywords: | ARF6, ADP-ribosylation factor 6 |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 20 kD |
540.00€
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Rab35 Q67L mutant (Member RAS oncogene family, RAY,...
Item number: NB-10133
The Ras super-family of small GTP-binding proteins, which includes the Ras, Ral, Rho, Rap, and Rab families, the Rab family appears to play a critical role in regulating exocytotic and endocytotic pathways. RAB35 regulates the assembly of actin filaments during bristle development in Drosophila and filopodia...
| Keywords: | RAB1C, RAB35, GTP-binding protein RAY, Ras-related protein Rab-35, Ras-related protein Rab-1C |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 23 kD |
397.00€
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G.alpha.13 (Guanine nucleotide-binding protein subunit...
Item number: NB-10138
Ga13 belongs to the G12 family of heterotrimeric guanine nucleotide-binding proteins, and has intrinsic GTPase activity. Ga13 has been revealed to play critical roles in transformation, normal hemostasis and thrombosis, growth factor-induced cell migration, angiogenesis, and salt-induced hypertension.
| Keywords: | GNA13, G alpha-13, G-protein subunit alpha-13, Guanine nucleotide-binding protein subunit alpha-13 |
| Expressed in: | Sf9 cells |
| Origin: | human |
| MW: | 44 kD |
384.00€
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Rab7 (Member RAS oncogene family, Rab7a, MGC102153),...
Item number: NB-10167
Members of the Rab family of Ras-related GTP-binding proteins are important regulators of vesicular transport and are located in specific intracellular compartments. Rab7 has been localized to late endosomes and shown to be important in the late endocytic pathway. In addition, it has been shown to have a fundamental...
| Keywords: | RAB7, RAB7A, Ras-related protein Rab-7a |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 23 kD |
369.00€
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