Teicoplanin complex is a mixture of closely related metabolites produced by A. teichomyceticus that are effective against Gram-positive bacteria. Teicoplanin A2, the major component of this complex, is a glycopeptide antibiotic structurally similar to vancomycin (Cay-15327) that prevents bacterial cell-wall...

Oritavancin is a semisynthetic glycopeptide antibiotic that inhibits the growth of Gram-positive bacteria. It inhibits transglycosylation and transpeptidation in the bacterial cell wall to disrupt membrane integrity. Oritavancin inhibits the growth of clinical isolates from skin and soft-tissue infections, including...

Teicoplanin A3-1 is a degradation product of teicoplanins A2-1 to 5 (Cay-20187, 20188, 20189, 20192). Teicoplanins are glycopeptide antibiotics produced by A. teichomyceticus that are broadly effective against Gram-positive bacteria in vitro.Formal Name:...

Teicoplanin A2-4 is a component of the teicoplanin complex (Cay-15511), a glycopeptide antibiotic produced by A. teichomyceticus that is broadly effective against Gram-positive bacteria in vitro.Formal Name:...

Teicoplanin A2-5 is a glycopeptide antibiotic produced by A. teichomyceticus that is broadly effective against Gram-positive bacteria in vitro. It is the most non-polar metabolite in the family of teicoplanins.Formal Name:...

Teicoplanin A2-3 is a major component of the teicoplanin complex (Cay-15511), a glycopeptide antibiotic produced by A. teichomyceticus that is broadly effective against Gram-positive bacteria in vitro.Formal Name:...

Aspartocin D is a lipopeptide antibiotic originally isolated from S. canus FIM0916. It has activity against Gram-positive bacteria, including B. subtilis and S. aureus (MICs = 0.125 and 0.5 µg/ml, respectively). The antibiotic activity is calcium-dependent, with MICs ranging from 0.06-4 and 0.25-8 µg/ml for B....

Vancomycin is a glycopeptide antibiotic identified for its utility in the treatment of gram-positive bacteria, including penicillin-resistant staphylococci. It acts by binding to bacterial cell wall protein precursors, interfering with continuing protein synthesis. Vancomycin resistance in staphylococcal species has...

Dalbavancin is a semisynthetic glycopeptide antibiotic. It inhibits the growth of Gram-positive bacteria in vitro, including S. pneumoniae, S. pyogenes, vancomycin-sensitive Enterococcus species, and various methicillin-resistant staphylococci (MIC50s = 0.03, =0.002, 0.13, and 0.03-0.13 mg/L, respectively)....

Parvodicin C2 is a glycopeptide antibiotic originally isolated from A. parvosata and a component of parvodicin complex (Cay-24036). It is also a component of the A40926 antibiotic complex, which has been used as a precursor in the synthesis of the antibiotic dalbavancin (Cay-21161). Parvodicin C2 is active against...