Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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TLT-1/TREML1 hFc Chimera, Mouse
Item number: GSC-Z06378-100
Triggering receptor expressed on myeloid cells (TREM)-like transcript-1 (TLT-1) is an immunoreceptor tyrosine-based inhibitory motif (ITIM)-baring TREM family protein. Triggering receptor expressed on myeloid cells (TREM) like transcript-1 (TLT-1) is a membrane protein receptor found in alpha-granules of platelets...
| Keywords: | Treml1, Trem-like transcript 1 protein, Triggering receptor expressed on myeloid cells-like protein 1 |
| Origin: | mouse |
| MW: | 43.61 kD |
From 457.00€
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TMEM106B hFc Chimera, Mouse
Item number: GSC-Z06379-100
TMEM106B is a well-recognised risk factor for FTD caused by GRN mutation. Elegant experiments have suggested that increased risk for FTD is due to elevated levels of TMEM106B (Nicholson et al, 2013, Gallagher et al, 2017). Therefore, recent work has explored the therapeutic potential of reducing TMEM106B levels,...
| Keywords: | Tmem106b, Transmembrane protein 106B |
| Origin: | mouse |
| MW: | 44.8 kD |
From 457.00€
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TNFRSF11A/Rank hFc Chimera, Mouse
Item number: GSC-Z06380-100
TNFRSF11A, also known as receptor activator of NF-kappaB (RANK), activates several signaling pathways, such as NF-kappaB, JNK, ERK, p38alpha, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in gliomas, which affects apoptotic activity and focus formation thereby contributing to the...
| Keywords: | Tnfrsf11a, Receptor activator of NF-KB, Osteoclast differentiation factor receptor, Tumor necrosis factor receptor... |
| Origin: | mouse |
| MW: | 47 kD |
From 524.00€
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VLDLR, His, Mouse
Item number: GSC-Z06401-100
VLDLR cerebellar hypoplasia (VLDLR-CH) is characterized by non-progressive congenital ataxia that is predominantly truncal and results in delayed ambulation, moderate-to-profound intellectual disability, dysarthria, strabismus, and seizures.VLDLR-CH is inherited in an autosomal recessive manner. Carrier testing for...
| Keywords: | Vldlr, Very low-density lipoprotein receptor |
| Origin: | mouse |
| MW: | 86.1 kD |
From 323.00€
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CDCP1, His, Rat
Item number: GSC-Z06413-100
Tumor metastasis depends on the dynamic regulation of cell adhesion through beta1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.
| Keywords: | Cdcp1, Cdcp1_predicted |
| Origin: | rat |
| MW: | 73.09 kD |
From 632.00€
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CKMT2, His, Rat
Item number: GSC-Z06414-100
Mitochondrial Creatine Kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine, and exists in mammals as two isoenzymes encoded by separate genes. In rats and humans, sarcomere-specific MtCK (sMtCK) is expressed only in skeletal and heart muscle,...
| Keywords: | Ckmt2, EC=2.7.3.2, Creatine kinase S-type, mitochondrial, Basic-type mitochondrial creatine kinase, Sarcomeric... |
| Origin: | rat |
| MW: | 44.48 kD |
From 524.00€
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Coagulation Factor II, His, Rat
Item number: GSC-Z06416-100
Prothrombin, or coagulation factor II, is a multidomain zymogen precursor of thrombin that undergoes an allosteric equilibrium between two alternative conformations, open and closed, that react differently with the physiological activator prothrombinase. It has 10 sites of gamma-carboxylation, which are required for...
| Keywords: | F2, Prothrombin, Coagulation factor II |
| Origin: | rat |
| MW: | 69.12 kD |
From 524.00€
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IL-13Ra2 hFc Chimera, Rat
Item number: GSC-Z06423-100
Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding...
| Keywords: | Il13ra2, Interleukin-13 receptor subunit alpha-2 |
| Origin: | rat |
| MW: | 63.17 kD |
From 457.00€
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IL-22R alpha 1 hFc Chimera, Rat
Item number: GSC-Z06424-100
Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), and NKT cells. IL-22 mediates its effects via a heterodimeric transmembrane receptor complex...
| Keywords: | Il22ra2, Interleukin-22-binding protein, Interleukin-22 receptor subunit alpha-2, Cytokine receptor family type 2, soluble 1 |
| Origin: | rat |
| MW: | 51.08 kD |
From 524.00€
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XPNPEP2, His, Rat
Item number: GSC-Z06433-100
Aminopeptidase P2 (XPNPEP2) is a receptor for TMTP1 tumor-homing peptide. However, the biological and clinical significance of Aminopeptidase P2 in human cancers remains unknown.
| Keywords: | Xpnpep2, Xaa-Pro aminopeptidase 2, X-prolyl aminopeptidase 2, Membrane-bound aminopeptidase P |
| Origin: | rat |
| MW: | 72.05 kD |
From 578.00€
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Complement Factor D/CFD, His, Rhesus macaque
Item number: GSC-Z06436-100
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal...
| Keywords: | CFD, Adipsin, Properdin factor D, Complement factor D, C3 convertase activator |
| Origin: | rhesus macaque |
| MW: | 25.7 kD |
From 524.00€
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KIR3DL3, His, Rhesus macaque
Item number: GSC-Z06443-100
Killer-cell immunoglobulin-like receptor (KIR) 3DL3 is a framework gene present in all human KIR haplotypes.KIR3DL3 has been shown to be constitutively expressed at a low RNA level in peripheral blood mononuclear cell (PBMC) and decidual natural kill (NK) cells.
| Keywords: | KIR3DL |
| Origin: | rhesus macaque |
| MW: | 35.39 kD |
From 524.00€
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