Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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NKp46/NCR1/CD335, His, Mouse
Item number: GSC-Z06282-100
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic...
| Keywords: | Ncr1, Activating receptor 1, Lymphocyte antigen 94, Natural killer cell p46-related protein, Natural cytotoxicity... |
| Origin: | mouse |
| MW: | 27.7 kD |
From 524.00€
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NPR1/NPRA, His, Mouse
Item number: GSC-Z06289-100
NPR1 (natriuretic peptide receptor 1), a receptor of ANP (atrial natriuretic peptide) whitch acting through NPR1, provokes hypotension. NPR1 was abundantly expressed in endothelial cells and smooth muscle cells of small arteries and arterioles. NPR1 plays a crucial role in ANP-mediated blood pressure regulation,...
| Keywords: | Npr1, Guanylate cyclase A, Atrial natriuretic peptide receptor 1, Atrial natriuretic peptide receptor type A |
| Origin: | mouse |
| MW: | 50.86 kD |
From 578.00€
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Oncostatin M/OSM, His, Mouse
Item number: GSC-Z06291-100
OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses...
| Keywords: | Osm, Oncostatin-M |
| Origin: | mouse |
| MW: | 21.64 kD |
From 497.00€
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OSMR beta, His, Mouse
Item number: GSC-Z06293-100
OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases...
| Keywords: | Osmr, Interleukin-31 receptor subunit beta, Oncostatin-M-specific receptor subunit beta |
| Origin: | mouse |
| MW: | 83.2 kD |
From 403.00€
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Osteoactivin/GPNMB, His, Mouse
Item number: GSC-Z06294-100
GPNMB is highly expressed in macrophages and microglia, which are cells involved with innate immune response in the periphery and the brain, respectively. Some studies have shown increased levels of GPNMB in pro-inflammatory conditions, such as LPS treatment, and in pathological conditions, such as neurodegenerative...
| Keywords: | Gpnmb, DC-HIL, Osteoactivin, Transmembrane glycoprotein NMB, Dendritic cell-associated transmembrane protein |
| Origin: | mouse |
| MW: | 54.7 kD |
From 497.00€
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OX40 Ligand/TNFSF4 hFc Chimera, Mouse
Item number: GSC-Z06295-100
Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L),which belongs to the tumor necrosis factor family. It is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation.
| Keywords: | Tnfsf4, OX40 ligand, Tumor necrosis factor ligand superfamily member 4 |
| Origin: | mouse |
| MW: | 42.6 kD |
From 551.00€
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PD-L1/B7-H1 hFc Chimera, Mouse
Item number: GSC-Z06301-100
B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune...
| Keywords: | Cd274, B7 homolog 1, Programmed cell death 1 ligand 1 |
| Origin: | mouse |
| MW: | 51.5 kD |
From 363.00€
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PRLR, His, Mouse
Item number: GSC-Z06320-100
Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe but with poor efficacy. It is therefore urgent to develop new therapies against PRLR target....
| Keywords: | Prlr, Prolactin receptor |
| Origin: | mouse |
| MW: | 25.7 kD |
From 457.00€
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PSAP/Prosaposin, His, Mouse
Item number: GSC-Z06323-100
Prosaposin (also known as SGP-1) is an intriguing multifunctional protein that plays roles both intracellularly, as a regulator of lysosomal enzyme function, and extracellularly, as a secreted factor with neuroprotective and glioprotective effects.
| Keywords: | Psca, Prostate stem cell antigen |
| Origin: | mouse |
| MW: | 60.86 kD |
From 524.00€
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P-Selectin/CD62P, His, Mouse
Item number: GSC-Z06326-100
P-selectin is critical in the progression of atherosclerosis as evidenced by knockout animal models where P-selectin knockout mice crossed with apoE deficient mice exhibit significantly reduced atherosclerosis and leukocyte recruitment in the plaque. A soluble form of P-selectin also exists, which may have...
| Keywords: | Selp, P-selectin, Granule membrane protein 140, CD62 antigen-like family member P, Leukocyte-endothelial cell adhesion... |
| Origin: | mouse |
| MW: | 81.1 kD |
From 349.00€
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PTK7/CCK4, His, Mouse
Item number: GSC-Z06330-100
Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system development, and also promotes human cancer formation. Observations in different model systems...
| Keywords: | Ptk7, Protein chuzhoi, Protein-tyrosine kinase 7, Tyrosine-protein kinase-like 7, Pseudo tyrosine kinase receptor 7,... |
| Origin: | mouse |
| MW: | 75.67 kD |
From 524.00€
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R spondin 1/RSPO1, His, Mouse
Item number: GSC-Z06333-100
The R-spondins are members of a superfamily of thrombospondin type 1 repeat (TSR-1)-containing proteins. The prototype member (discovered in 1971) was isolated from platelets that had been stimulated with thrombin, and was therefore designated 'thrombin-sensitive protein.
| Keywords: | Rspo1, R-spondin-1, Roof plate-specific spondin-1, Cysteine-rich and single thrombospondin domain-containing protein 3 |
| Origin: | mouse |
| MW: | 28.3 kD |
From 632.00€
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