Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer, His,...
Item number: GSC-Z06219-100
Integrin alpha1beta1 is a heterodimer of the Integrin subunits alpha 1 and beta 1 and is one of four collagen-binding integrins, it preferentially binds Collagens I, IV, VI, XIII and XVI, but also binds Laminin. Integrin alpha1beta1 is widely expressed in mesenchyme and the immune system, as well as a minority of...
| Keywords: | Itgb1, Integrin beta-1, VLA-4 subunit beta, Fibronectin receptor subunit beta |
| Origin: | mouse |
| MW: | 129.00/2.8 kD |
From 632.00€
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ITK, His & GST & Strep-II, Mouse
Item number: GSC-Z06229-100
ITK (IL-2-inducible tyrosine kinase) belongs to the Tec family kinases and is mainly expressed in T cells. It is involved in TCR signalling events driving processes like T cell development as well as Th2, Th9 and Th17 responses thereby controlling the expression of pro-inflammatory cytokines.
| Keywords: | Itk, Kinase TLK, Kinase EMT, T-cell-specific kinase, IL-2-inducible T-cell kinase, Tyrosine-protein kinase ITK/TSK |
| Origin: | mouse |
| MW: | 61.42 kD |
From 497.00€
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Latent TGF beta 1/TGFB1, His, Mouse
Item number: GSC-Z06239-100
Latent TGF beta 1 cDNA encodes a 390 amino acid precursor that contains a 29 aa signal peptide and a 361 aa proprotein. A furin-like convertase processes the proprotein to generate an N-terminal 249 aa latency-associated peptide (LAP) and a C-terminal 112 aa mature TGF- beta 1. Disulfide-linked homodimers of LAP and...
| Keywords: | Tgfb1, Transforming growth factor beta-1 proprotein |
| Origin: | mouse |
| MW: | 29.5/12.9 kD |
From 578.00€
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LGMN, His, Mouse
Item number: GSC-Z06242-100
Recently, functional studies have demonstrated that legumain (LGMN) cleaves both amyloid beta-protein precursor and tau, promoting senile plaques and formation of neurofibrillary tangles, which may play a crucial role in the pathogenesis of Alzheimer's disease (AD). In single-variant association analysis, none of...
| Keywords: | Lgmn, Legumain, Protease, cysteine 1 |
| Origin: | mouse |
| MW: | 48.6 kD |
From 403.00€
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LRP10, His, Mouse
Item number: GSC-Z06249-100
LDL receptor-related protein (LRP) 10 was recently identified as a Parkinson's disease gene through genome-wide linkage and sequencing analysis, but its role in Parkinson's disease in various populations is still unclear.
| Keywords: | Lrp10, Low-density lipoprotein receptor-related protein 10 |
| Origin: | mouse |
| MW: | 46.88 kD |
From 457.00€
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LTBR hFc Chimera, Mouse
Item number: GSC-Z06252-100
Components of lymphotoxin beta receptor (LTBR)-associated signaling complexes, including TRAF2, TRAF3, NIK, IKK1, and IKK2 have been shown to participate in the coupling of LTBR to NFkappaB. TRAF3 functions as a negative regulator of LTBR signaling via both canonical and non-canonical NFkappaB pathways by two...
| Keywords: | Ltbr, Lymphotoxin-beta receptor, Tumor necrosis factor receptor superfamily member 3 |
| Origin: | mouse |
| MW: | 48.5 kD |
From 255.00€
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MANSC1, His, Mouse
Item number: GSC-Z06259-100
MANSC1 contains 1 MANSC domain. MANSC is a seven-cysteine-containing domain present in animal membrane and extracellular proteins. MANSC (motif at N terminus with seven cysteines) is a novel domain with a well-conserved seven-cysteine motif that is present at the N terminus of membrane and extracellular proteins,...
| Keywords: | Mansc1, MANSC domain-containing protein 1 |
| Origin: | mouse |
| MW: | 38.2 kD |
From 457.00€
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M-CSF R/CSF1R/CD115, His, Mouse
Item number: GSC-Z06263-100
CSF1R also known as M-CSF receptor, the product of the c-fms proto-oncogene, is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in...
| Keywords: | Csf1r, CSF-1 receptor, Proto-oncogene c-Fms, Macrophage colony-stimulating factor 1 receptor |
| Origin: | mouse |
| MW: | 56.3 kD |
From 497.00€
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MDL-1/CLEC5A hFc Chimera, Mouse
Item number: GSC-Z06264-100
In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, is an inhibitor of cell proliferation and growth that slows progression of an age-related...
| Keywords: | Clec5a, C-type lectin superfamily member 5, Myeloid DAP12-associating lectin 1, C-type lectin domain family 5 member A |
| Origin: | mouse |
| MW: | 46.2 kD |
From 403.00€
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MEPE, His, Mouse
Item number: GSC-Z06265-100
Matrix extracellular phosphoglycoprotein (MEPE) is expressed in bone and teeth where it has multiple functions. The C-terminus of MEPE contains a mineral-binding, acidic serine- and aspartate-rich motif (ASARM) that is also present in other noncollagenous proteins of mineralized tissues.MEPE-derived ASARM peptides...
| Keywords: | Mepe, Osteoregulin, Osteoblast/osteocyte factor 45, Matrix extracellular phosphoglycoprotein |
| Origin: | mouse |
| MW: | 45.3 kD |
From 457.00€
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MMP-9, His, Mouse
Item number: GSC-Z06272-100
Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demonstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds. To...
| Keywords: | Mmp9, Gelatinase B, 92 kDa gelatinase, Matrix metalloproteinase-9, 92 kDa type IV collagenase |
| Origin: | mouse |
| MW: | 79.64 kD |
From 497.00€
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NGAL/Lipocalin-2 hFc Chimera, Mouse
Item number: GSC-Z06279-100
Acute kidney injury (AKI) is one of the most common complications of various serious conditions, and early diagnosis is therefore critical for the treatment of AKI. Recent evidence demonstrates that neutrophil gelatinase- associated lipocalin (NGAL) is closely associated with AKI. Several experimental and clinical...
| Keywords: | p25, Lcn2, Lipocalin-2, Oncogene 24p3, Siderocalin LCN2, SV-40-induced 24p3 protein, Neutrophil gelatinase-associated... |
| Origin: | mouse |
| MW: | 47.5 kD |
From 578.00€
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