Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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EPHB2, His, Mouse
Item number: GSC-Z06104-100
EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated pathologic characteristics of glioblastoma multiforme (GBM) such as invasion and migration. EPHB2...
| Keywords: | Ephb2, Neural kinase, Ephrin type-B receptor 2, Nuk receptor tyrosine kinase, Tyrosine-protein kinase receptor EPH-3,... |
| Origin: | mouse |
| MW: | 59.3 kD |
From 403.00€
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EphB3, His, Mouse
Item number: GSC-Z06105-100
Although EphB3 expression is down-regulated in colorectal cancer (CRC) cells compared with normal intestinal epithelial cells.EphB3 is down-regulated in CRC compared to normal mucosa. Hypermethylation of CpG island is contributed to downregulation of EphB3 in CRC. EphB3 expression in tumor cells may be a useful...
| Keywords: | Ephb3, Developmental kinase 5, Ephrin type-B receptor 3, Tyrosine-protein kinase receptor SEK-4 |
| Origin: | mouse |
| MW: | 58.4 kD |
From 457.00€
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Fas/TNFRSF6/CD95 hFc Chimera, Mouse
Item number: GSC-Z06113-100
CD95 (also known as Fas) is a member of the tumor necrosis factor receptor (TNFR) superfamily. Its cognate ligand, CD95L, is implicated in immune homeostasis and immune surveillance. Mutations in this receptor are associated with a loss of apoptotic signaling and have been detected in an autoimmune disorder called...
| Keywords: | Fas, Apo-1 antigen, FASLG receptor, Apoptosis-mediating surface antigen FAS, Tumor necrosis factor receptor superfamily... |
| Origin: | mouse |
| MW: | 43.3 kD |
From 296.00€
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FGFR3 alpha (IIIb), His, Mouse
Item number: GSC-Z06121-100
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the...
| Keywords: | Fgfr3, Fibroblast growth factor receptor 3, Heparin-binding growth factor receptor |
| Origin: | mouse |
| MW: | 37.09 kD |
From 457.00€
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FGL2, His & Avi & Flag, Mouse
Item number: GSC-Z06122-100
Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. FGL2 is overexpressed in glioma, and its expression level is negatively associated with the prognosis of glioma patients.
| Keywords: | Fgl2, Fibroleukin, Prothrombinase, Fibrinogen-like protein 2, Cytotoxic T-lymphocyte-specific protein |
| Origin: | mouse |
| MW: | 31.48 kD |
From 578.00€
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FOLR2, His, Mouse
Item number: GSC-Z06126-100
FOLR1 and FOLR2 are equipped with cellular glycosylphosphatidylinositol (GPI) anchors. FOLR1 is secreted from epithelia with or without a micelle-encapsulated GPI-anchor into milk and other body fluids/secretions, e.g. semen where its interaction with spermatozoa indicates a role in male fertility. FOLR1 and FOLR2...
| Keywords: | Folr2, Folate receptor 2, Folate receptor beta, Folate-binding protein 2 |
| Origin: | mouse |
| MW: | 25.3 kD |
From 255.00€
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FSH alpha&beta, His, Mouse
Item number: GSC-Z06128-100
FSH (Follicle-stimulating hormone) is a gonadotropin, a glycoprotein polypeptide hormone. It has a functionally indispensable 96 amino acid alpha subunit that is common to LH, TSH and hCG, in addition to a structurally unique beta subunit. FSH is synthesized and secreted by the gonadotropic cells of the anterior...
| Keywords: | Fshb, Follitropin beta chain, Follitropin subunit beta, Follicle-stimulating hormone beta subunit |
| Origin: | mouse |
| MW: | 12.28/3.67 kD |
From 524.00€
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FSHB hFc Chimera, Mouse
Item number: GSC-Z06129-100
Fertility is dependent on follicle-stimulating hormone (FSH), a product of gonadotrope cells of the anterior pituitary gland. Hypothalamic gonadotropin-releasing hormone (GnRH) and intra-pituitary activins are regarded as the primary drivers of FSH synthesis and secretion. Both stimulate expression of the FSH beta...
| Keywords: | Fshb, Follitropin beta chain, Follitropin subunit beta, Follicle-stimulating hormone beta subunit |
| Origin: | mouse |
| MW: | 39.2 kD |
From 457.00€
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GARP&Latent TGF beta 1 Complex, His, Mouse
Item number: GSC-Z06134-100
GARP&Latent TGF Beta is a complex found on surface of many types of cells. In Tregs, GARP is involved in TCR-mediated activation of Latent TGF-beta and thus promoting secretion and activation of TGF-beta. Integrin alphavbeta8 on the surface of immune cells and other cells recognizes RGD in LAP, resulting in the...
| Keywords: | Tgfb1, Transforming growth factor beta-1 proprotein |
| Origin: | mouse |
| MW: | 66.6/41.3 kD |
From 524.00€
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G-CSF R/CD114, His, Mouse
Item number: GSC-Z06136-100
The Granulocyte Colony-Stimulating Factor (G-CSF) receptor, a member of the hematopoietin cytokine receptor superfamily, functions as a homodimer and requires the recruitment of cytosolic protein tyrosine kinases (PTKs) to transduce its signal.
| Keywords: | Csf3r, Granulocyte colony-stimulating factor receptor |
| Origin: | mouse |
| MW: | 68.47 kD |
From 457.00€
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GEP, His, Mouse
Item number: GSC-Z06139-100
Haploinsufficiency of progranulin (PGRN) is a leading cause of frontotemporal lobar degeneration (FTLD). Loss of PGRN leads to lysosome dysfunction during aging. TMEM106B, a gene encoding a lysosomal membrane protein, is the main risk factor for FTLD with PGRN haploinsufficiency.Loss of both PGRN and TMEM106B...
| Keywords: | Grn, Acrogranin, Progranulin, Proepithelin, Glycoprotein of 88 Kda, Epithelin/granulin precursor, PC cell-derived growth... |
| Origin: | mouse |
| MW: | 62.7 kD |
From 457.00€
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GIP, His, Mouse
Item number: GSC-Z06142-100
The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic use of GIP was dampened by evidence that its insulinotropic activity was reduced in type 2...
| Keywords: | Gip, Gastric inhibitory polypeptide, Glucose-dependent insulinotropic polypeptide |
| Origin: | mouse |
| MW: | 8.7 kD |
From 457.00€
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