Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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TFPI, His & Avi, Human
Item number: GSC-Z05869-100
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and has recently been associated with breast cancer cell development.
| Keywords: | TFPI, Extrinsic pathway inhibitor, Tissue factor pathway inhibitor, Lipoprotein-associated coagulation inhibitor |
| Origin: | human |
| MW: | 32.1 kD |
From 484.00€
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TGF-beta RII/TGFBR2 hFc Chimera, Human
Item number: GSC-Z05873-100
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-beta) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects...
| Keywords: | TGFBR2, TGF-beta receptor type-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II |
| Origin: | human |
| MW: | 44.2 kD |
From 497.00€
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TGFBR1, mFc Chimera, Avi, Human
Item number: GSC-Z05874-100
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR-98-5p. miR-98-5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells.
| Keywords: | TGFBR1, TGF-beta type I receptor, TGF-beta receptor type-1, Activin receptor-like kinase 5, Serine/threonine-protein... |
| Origin: | human |
| MW: | 38.2 kD |
From 497.00€
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TIMP-2, His, Human
Item number: GSC-Z05887-100
Tissue inhibitors of metalloproteinases or TIMPs are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs).TIMP-2 is a non N-glycosylated protein with a molecular mass of 22 kDa produced by a wide range of cell types, which inhibits...
| Keywords: | TIMP2, CSC-21K, Metalloproteinase inhibitor 2, Tissue inhibitor of metalloproteinases 2 |
| Origin: | human |
| MW: | 22.9 kD |
From 403.00€
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TLR3, His, Human
Item number: GSC-Z05888-100
TLR3 is expressed in the central nervous system (CNS), where it is required to control HSV-1, which spreads from the epithelium to the CNS via cranial nerves. TLR3 is also expressed in epithelial and dendritic cells, which apparently use TLR3-independent pathways to prevent further dissemination of HSV-1 and to...
| Keywords: | TLR3, Toll-like receptor 3 |
| Origin: | human |
| MW: | 78.7 kD |
From 497.00€
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TLT-1/TREML1 hFc Chimera, Human
Item number: GSC-Z05889-100
Triggering receptor expressed on myeloid cells (TREM)-like transcript-1 (TLT-1) is an immunoreceptor tyrosine-based inhibitory motif (ITIM)-baring TREM family protein. Triggering receptor expressed on myeloid cells (TREM) like transcript-1 (TLT-1) is a membrane protein receptor found in alpha-granules of platelets...
| Keywords: | TREML1, Trem-like transcript 1 protein, Triggering receptor expressed on myeloid cells-like protein 1 |
| Origin: | human |
| MW: | 42.6 kD |
From 457.00€
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TNFR1/CD120a/TNFRSF1A, His, Human
Item number: GSC-Z05893-100
Tumour necrosis factor alpha (TNF-alpha) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of acute injury, selective inhibition of TNFR1 is predicted to attenuate the cell death and...
| Keywords: | p55, p60, TNFRSF1A, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type I, Tumor necrosis factor... |
| Origin: | human |
| MW: | 23.3 kD |
From 363.00€
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TNFR2/CD120b/TNFRSF1B hFc Chimera, Human
Item number: GSC-Z05894-100
Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for...
| Keywords: | p75, TNFRSF1B, p80 TNF-alpha receptor, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor type II, Tumor... |
| Origin: | human |
| MW: | 51.89 kD |
From 403.00€
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TNFSF15, Fc Chimera, Human
Item number: GSC-Z05903-100
TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates...
| Keywords: | TNFSF15, TNF ligand-related molecule 1, Vascular endothelial cell growth inhibitor, Tumor necrosis factor ligand... |
| Origin: | human |
| MW: | 44.87 kD |
From 497.00€
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tPA, His, Human
Item number: GSC-Z05906-100
Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the predominant route for enhancing cell survival is via an mTORdependent mechanism.
| Keywords: | PLAT, Tissue-type plasminogen activator |
| Origin: | human |
| MW: | 60.13 kD |
From 457.00€
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TRAIL R1/DR4/TNFRSF10A hFc Chimera, Human
Item number: GSC-Z05910-100
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a wide range of cancers, while sparing normal cells. Despite its tremendous potential for cancer therapeutics, the translation of TRAIL into...
| Keywords: | TNFRSF10A, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, Tumor necrosis factor receptor superfamily... |
| Origin: | human |
| MW: | 48.8 kD |
From 363.00€
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TRAIL R1/DR4/TNFRSF10A, His & Avi, Human
Item number: GSC-Z05911-100
Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily.The expression of apoptosis-inducing TRAIL-R1 and TRAIL-R2 and of the decoy receptors TRAIL-R3 and...
| Keywords: | TNFRSF10A, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, Tumor necrosis factor receptor superfamily... |
| Origin: | human |
| MW: | 24.7 kD |
From 363.00€
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